KEGG   ENZYME: 3.4.22.26Help
Entry
EC 3.4.22.26                Enzyme                                 

Name
cancer procoagulant
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Cysteine endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Specific cleavage of Arg!Ile bond in Factor X to form Factor Xa
Comment
Apparently produced only by malignant and fetal cells
History
EC 3.4.22.26 created 1992
Reference
1  [PMID:3935163]
  Authors
Falanga A, Gordon SG.
  Title
Isolation and characterization of cancer procoagulant: a cysteine proteinase from malignant tissue.
  Journal
Biochemistry. 24 (1985) 5558-67.
Reference
2  [PMID:2772865]
  Authors
Falanga A, Shaw E, Donati MB, Consonni R, Barbui T, Gordon S.
  Title
Inhibition of cancer procoagulant by peptidyl diazomethyl ketones and peptidyl sulfonium salts.
  Journal
Thromb. Res. 54 (1989) 389-98.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
109456-80-6

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