KEGG   ENZYME: 3.4.23.35Help
Entry
EC 3.4.23.35                Enzyme                                 

Name
barrierpepsin;
barrier proteinase;
Bar proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Aspartic endopeptidases
BRITE hierarchy
Reaction(IUBMB)
Selective cleavage of -Leu6!Lys- bond in the pheromone alpha-mating factor
Comment
A secreted endopeptidase known from baker's yeast (Saccharomyces cerevisiae). In peptidase family A1 (pepsin A family)
History
EC 3.4.23.35 created 1993
Orthology
K01383  
barrierpepsin
Genes
SCE: 
YIL015W(BAR1)
AGO: 
ERC: 
KLA: 
ZRO: 
CGR: 
NCS: 
NCAS_0A12460(NCAS0A12460)
NDI: 
NDAI_0B01720(NDAI0B01720)
TBL: 
TBLA_0D04580(TBLA0D04580)
TDL: 
TDEL_0H02650(TDEL0H02650)
Taxonomy
Reference
1  [PMID:3124102]
  Authors
MacKay VL, Welch SK, Insley MY, Manney TR, Holly J, Saari GC, Parker ML.
  Title
The Saccharomyces cerevisiae BAR1 gene encodes an exported protein with homology to pepsin.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 85 (1988) 55-9.
  Sequence
[sce:YIL015W]
Reference
2  [PMID:1812704]
  Authors
MacKay VL, Armstrong J, Yip C, Welch S, Walker K, Osborn S, Sheppard P, Forstrom J.
  Title
Characterization of the Bar proteinase, an extracellular enzyme from the yeast Saccharomyces cerevisiae.
  Journal
Adv. Exp. Med. Biol. 306 (1991) 161-72.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
152060-38-3

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