| Entry |
|
| Name |
envelysin;
sea-urchin-hatching proteinase;
hatching enzyme;
chorionase;
chorion-digesting proteinase;
chymostrypsin;
sea urchin embryo hatching enzyme
|
| Class |
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
 |
| Reaction(IUBMB) |
Hydrolysis of proteins of the fertilization envelope and dimethylcasein
|
| Comment |
A glycoprotein from various members of the class Echinoidea. Extracellular enzyme requiring Ca2+. In peptidase family M10 (interstitial collagenase family)
|
| Reference |
|
| Authors |
Barrett D, Edwards BF. |
| Title |
Hatching enzyme of the sea urchin Strongylocentrotus purpuratus. |
| Journal |
Methods. Enzymol. 45 (1976) 354-73. |
| Organism |
Strongylocentrotus purpuratus [GN: spu] |
| Reference |
|
| Authors |
Lepage T, Gache C. |
| Title |
Purification and characterization of the sea urchin embryo hatching enzyme. |
| Journal |
J. Biol. Chem. 264 (1989) 4787-93. |
| Organism |
Paracentrotus lividus |
| Reference |
|
| Authors |
Lepage T, Gache C. |
| Title |
Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo. |
| Journal |
EMBO. J. 9 (1990) 3003-12. |
| Organism |
Paracentrotus lividus |
| Reference |
|
| Authors |
Nomura K, Tanaka H, Kikkawa Y, Yamaguchi M, Suzuki N. |
| Title |
The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family. |
| Journal |
Biochemistry. 30 (1991) 6115-23. |
| Organism |
Hemicentrotus pulcherrimus |
| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 50812-13-0 |