KEGG   ENZYME: 3.4.24.12Help
Entry
EC 3.4.24.12                Enzyme                                 

Name
envelysin;
sea-urchin-hatching proteinase;
hatching enzyme;
chorionase;
chorion-digesting proteinase;
chymostrypsin;
sea urchin embryo hatching enzyme
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolysis of proteins of the fertilization envelope and dimethylcasein
Comment
A glycoprotein from various members of the class Echinoidea. Extracellular enzyme requiring Ca2+. In peptidase family M10 (interstitial collagenase family)
Reference
1  [PMID:1012003]
  Authors
Barrett D, Edwards BF.
  Title
Hatching enzyme of the sea urchin Strongylocentrotus purpuratus.
  Journal
Methods. Enzymol. 45 (1976) 354-73.
  Organism
Strongylocentrotus purpuratus [GN:spu]
Reference
2  [PMID:2925668]
  Authors
Lepage T, Gache C.
  Title
Purification and characterization of the sea urchin embryo hatching enzyme.
  Journal
J. Biol. Chem. 264 (1989) 4787-93.
  Organism
Paracentrotus lividus
Reference
3  [PMID:2167841]
  Authors
Lepage T, Gache C.
  Title
Early expression of a collagenase-like hatching enzyme gene in the sea urchin embryo.
  Journal
EMBO. J. 9 (1990) 3003-12.
  Organism
Paracentrotus lividus
Reference
4  [PMID:1711895]
  Authors
Nomura K, Tanaka H, Kikkawa Y, Yamaguchi M, Suzuki N.
  Title
The specificity of sea urchin hatching enzyme (envelysin) places it in the mammalian matrix metalloproteinase family.
  Journal
Biochemistry. 30 (1991) 6115-23.
  Organism
Hemicentrotus pulcherrimus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
50812-13-0

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