KEGG   ENZYME: 3.4.24.35Help
Entry
EC 3.4.24.35                Enzyme                                 

Name
gelatinase B;
92-kDa gelatinase;
matrix metalloproteinase 9;
type V collagenase;
92-kDa type IV collagenase;
macrophage gelatinase;
95 kDa type IV collagenase/gelatinase;
collagenase IV (ambiguous);
collagenase type IV (ambiguous);
gelatinase MMP 9;
MMP 9;
type IV collagen metalloproteinase (ambiguous)
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Cleavage of gelatin types I and V and collagen types IV and V
Comment
Similar to gelatinase A, but possesses a further domain . In peptidase family M10 (interstitial collagenase family)
History
EC 3.4.24.35 created 1992
Orthology
K01403  matrix metalloproteinase-9 (gelatinase B)
Genes
HSA: 4318(MMP9)
PTR: 458294(MMP9)
PPS: 100974722(MMP9)
GGO: 101138361(MMP9)
PON: 100455867(MMP9)
NLE: 100587873(MMP9)
MCC: 708084(MMP9)
MCF: 102117693(MMP9)
CSAB: 103245064(MMP9)
RRO: 104678814(MMP9)
RBB: 108533326(MMP9)
CJC: 100415095(MMP9)
SBQ: 101036569(MMP9)
MMU: 17395(Mmp9)
RNO: 81687(Mmp9)
CGE: 100770707(Mmp9)
NGI: 103751232(Mmp9)
HGL: 101717243(Mmp9)
CCAN: 109689278(Mmp9)
OCU: 100008993(MMP9)
TUP: 102487885(MMP9)
CFA: 403885(MMP9)
AML: 100475429(MMP9)
UMR: 103669705(MMP9)
ORO: 101380511(MMP9)
FCA: 101084185(MMP9)
PTG: 102959269(MMP9)
AJU: 106969010(MMP9)
BTA: 282871(MMP9)
BOM: 102273141(MMP9)
BIU: 109567506(MMP9)
PHD: 102321866(MMP9)
CHX: 102168469(MMP9)
OAS: 100192422(MMP9)
SSC: 654325(MMP9)
CFR: 102509767(MMP9)
CDK: 105087845(MMP9)
BACU: 103016628(MMP9)
LVE: 103086240(MMP9)
OOR: 101277919(MMP9)
ECB: 100056599(MMP9)
EPZ: 103551921(MMP9)
EAI: 106843045(MMP9)
MYB: 102260281(MMP9)
MYD: 102765342(MMP9)
HAI: 109379910(MMP9)
RSS: 109457039(MMP9)
PALE: 102889517(MMP9)
LAV: 100664260(MMP9)
TMU: 101347888
MDO: 100022144(MMP9)
SHR: 100934566(MMP9)
GGA: 395387(MMP9)
MGP: 100540313(MMP9)
CJO: 107323128(MMP9)
APLA: 101793782(MMP9)
ACYG: 106047143(MMP9)
TGU: 100227728(MMP9)
GFR: 102042403(MMP9)
FAB: 101813444(MMP9)
PHI: 102112681(MMP9)
PMAJ: 107213224(MMP9)
CCW: 104687728(MMP9)
FPG: 101912755(MMP9)
FCH: 102053895(MMP9)
CLV: 102094215(MMP9)
EGZ: 104127957(MMP9)
AAM: 106497585(MMP9)
ASN: 102368987(MMP9)
AMJ: 106736975(MMP9)
PSS: 106732917(MMP9)
CPIC: 101936391(MMP9)
PBI: 103064710(MMP9)
GJA: 107114269 107114899(MMP9) 107125021(ELSPBP1)
XLA: 100037129(mmp9.L) 108702732 379663(mmp9.S)
XTR: 100494738(mmp9) 448591(mmp9)
NPR: 108789114(MMP9)
DRE: 406397(mmp9)
IPU: 100304980(mmp9) 108265954
AMEX: 103023931
TRU: 653023(mmp9)
LCO: 104926671(mmp9)
NCC: 104964418(mmp9)
MZE: 101483885(mmp9)
OLA: 100125420(mmp9)
XMA: 102229854(mmp9)
NFU: 107390812(mmp9)
CSEM: 103384600(mmp9)
LCF: 108876510(mmp9)
BPEC: 110164611(mmp9)
SASA: 100195428(mmp9) 106566399
ELS: 105023758(mmp9)
SFM: 108931255(mmp9)
LCM: 102358076(MMP9)
CMK: 103191321(mmp9)
 » show all
Taxonomy
Reference
1  [PMID:3680518]
  Authors
Hibbs MS, Hoidal JR, Kang AH.
  Title
Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages.
  Journal
J. Clin. Invest. 80 (1987) 1644-50.
Reference
2  [PMID:2551898]
  Authors
Wilhelm SM, Collier IE, Marmer BL, Eisen AZ, Grant GA, Goldberg GI.
  Title
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages.
  Journal
J. Biol. Chem. 264 (1989) 17213-21.
  Sequence
[hsa:4318]
Reference
3  [PMID:2165210]
  Authors
Mainardi CL, Hasty KA.
  Title
Secretion and glycosylation of rabbit macrophage type V collagenase.
  Journal
Matrix. 10 (1990) 84-90.
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.35
IUBMB Enzyme Nomenclature: 3.4.24.35
ExPASy - ENZYME nomenclature database: 3.4.24.35
BRENDA, the Enzyme Database: 3.4.24.35
CAS: 146480-36-6

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