KEGG   ENZYME: 3.4.24.43Help
Entry
EC 3.4.24.43                Enzyme                                 

Name
atroxase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Cleavage of His5!Leu, Ser9!His, His10!Leu, Ala14!Leu and Tyr16!Leu of insulin B chain
Comment
A nonhemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that cleaves fibrinogen. In peptidase family M12 (astacin family)
History
EC 3.4.24.43 created 1992
Reference
1  [PMID:3167016]
  Authors
Willis TW, Tu AT.
  Title
Purification and biochemical characterization of atroxase, a nonhemorrhagic fibrinolytic protease from western diamondback rattlesnake venom.
  Journal
Biochemistry. 27 (1988) 4769-77.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
181186-94-7

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