KEGG   ENZYME: 3.4.24.53Help
Entry
EC 3.4.24.53                Enzyme                                 

Name
trimerelysin II;
Trimeresurus metalloendopeptidase II;
proteinase H2;
H2-proteinase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Cleavage of Asn3!Gln, His10!Leu and Ala14!Leu in the insulin B chain, and the bond Z-Gly-Pro!Leu-Gly-Pro in a small molecule substrate of microbial collagenase
Comment
A 24 kDa nonhemorrhagic endopeptidase from the venom of the habu snake (Trimeresurus flavoviridis). In peptidase family M12 (astacin family)
History
EC 3.4.24.53 created 1992
Reference
1  [PMID:4984550]
  Authors
Takahashi T, Ohsaka A.
  Title
Purification and characterization of a proteinase in the venom of Trimeresurus flavoviridis. Complete separation of the enzyme from hemorrhagic activity.
  Journal
Biochim. Biophys. Acta. 198 (1970) 293-307.
Reference
2  [PMID:2777746]
  Authors
Takeya H, Arakawa M, Miyata T, Iwanaga S, Omori-Satoh T.
  Title
Primary structure of H2-proteinase, a non-hemorrhagic metalloproteinase, isolated from the venom of the habu snake, Trimeresurus flavoviridis.
  Journal
J. Biochem. (Tokyo). 106 (1989) 151-7.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
151125-15-4

DBGET integrated database retrieval system