KEGG   ENZYME: 3.4.24.76Help
Entry
EC 3.4.24.76                Enzyme                                 

Name
flavastacin
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metalloendopeptidases
BRITE hierarchy
Reaction(IUBMB)
Hydrolyses polypeptides on the amino-side of Asp in -Xaa!Asp-. Acts very slowly on -Xaa!Glu
Comment
A zinc metalloendopeptidase in peptidase family M12 (astacin family), secreted by the bacterium Flavobacterium meningosepticum . The specificity is similar to that of EC 3.4.24.33, peptidyl-Asp metalloendopeptidase from Pseudomonas fragi but the two are reported to be structurally dissimilar
History
EC 3.4.24.76 created 2000
Orthology
K20138  flavastacin
Genes
EAO: BD94_1887
EMN: M876_06475
ELB: VO54_00855
Taxonomy
Reference
1  [PMID:7771796]
  Authors
Tarentino AL, Quinones G, Grimwood BG, Hauer CR, Plummer TH Jr.
  Title
Molecular cloning and sequence analysis of flavastacin: an O-glycosylated prokaryotic zinc metalloendopeptidase.
  Journal
Arch. Biochem. Biophys. 319 (1995) 281-5.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.4.24.76
IUBMB Enzyme Nomenclature: 3.4.24.76
ExPASy - ENZYME nomenclature database: 3.4.24.76
BRENDA, the Enzyme Database: 3.4.24.76
CAS: 167973-66-2

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