KEGG   ENZYME: 3.5.1.101Help
Entry
EC 3.5.1.101                Enzyme                                 

Name
L-proline amide hydrolase;
S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase;
LaaA;
L-amino acid amidase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
(S)-piperidine-2-carboxamide amidohydrolase
Reaction(IUBMB)
(1) (S)-piperidine-2-carboxamide + H2O = (S)-piperidine-2-carboxylic acid + NH3 [RN:R09680];
(2) L-prolinamide + H2O = L-proline + NH3 [RN:R09650]
Reaction(KEGG)
R09650 R09680;
(other) R09649
Show
Substrate
(S)-piperidine-2-carboxamide [CPD:C19809];
H2O [CPD:C00001];
L-prolinamide [CPD:C19781]
Product
(S)-piperidine-2-carboxylic acid [CPD:C00408];
NH3 [CPD:C00014];
L-proline [CPD:C00148]
History
EC 3.5.1.101 created 2009
Reference
1  [PMID:15066172]
  Authors
Komeda H, Harada H, Washika S, Sakamoto T, Ueda M, Asano Y
  Title
S-stereoselective piperazine-2-tert-butylcarboxamide hydrolase from Pseudomonas azotoformans IAM 1603 is a novel L-amino acid amidase.
  Journal
Eur. J. Biochem. 271 (2004) 1465-75.
  Organism
Pseudomonas azotoformans
  Sequence
[up:Q76KX0]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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