KEGG   ENZYME: 3.5.1.116Help
Entry
EC 3.5.1.116                Enzyme                                 

Name
ureidoglycolate amidohydrolase;
ureidoglycolate hydrolase;
UAH (gene name)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
(S)-ureidoglycolate amidohydrolase (decarboxylating)
Reaction(IUBMB)
(S)-ureidoglycolate + H2O = glyoxylate + 2 NH3 + CO2 [RN:R00469]
Reaction(KEGG)
Substrate
(S)-ureidoglycolate [CPD:C00603];
H2O [CPD:C00001]
Product
glyoxylate [CPD:C00048];
NH3 [CPD:C00014];
CO2 [CPD:C00011]
Comment
This plant enzyme is involved in the degradation of ureidoglycolate, an intermediate of purine degradation. Not to be confused with EC 4.3.2.3, ureidoglycolate lyase, which releases urea rather than ammonia.
History
EC 3.5.1.116 created 1992 as EC 3.5.3.19, transferred 2014 to EC 3.5.1.116
Pathway
Purine metabolism
Metabolic pathways
Microbial metabolism in diverse environments
Orthology
K18151  
ureidoglycolate amidohydrolase
Genes
ATH: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj5g3v1174280.1(Lj5g3v1174280.1) Lj5g3v1174280.2(Lj5g3v1174280.2)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0010s08660g(POPTRDRAFT_769208)
VVI: 
SLY: 
SPEN: 
SIND: 
BVG: 
NNU: 
OSA: 
4352706(OsJ_36749)
DOSA: 
Os12t0597500-01(Os12g0597500)
OBR: 
BDI: 
ATS: 
SBI: 
SORBI_08g020250(SORBIDRAFT_08g020250)
ZMA: 
100279195(GRMZM2G130034)
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
BPG: 
MIS: 
CSL: 
CVR: 
APRO: 
GSL: 
CCP: 
SAMY: 
CBUT: 
LACY: 
TRA: 
MRB: 
MRE: 
MSV: 
MIN: 
Minf_2338(argE)
PHM: 
TPX: 
ACM: 
GMA: 
TSA: 
TRS: 
SUS: 
ABAC: 
 » show all
Taxonomy
Reference
1  [PMID:16666035]
  Authors
Winkler RG, Blevins DG, Randall DD.
  Title
Ureide Catabolism in Soybeans : III. Ureidoglycolate Amidohydrolase and Allantoate Amidohydrolase Are Activities of an Allantoate Degrading Enzyme Complex.
  Journal
Plant. Physiol. 86 (1988) 1084-1088.
Reference
2  [PMID:1910298]
  Authors
Wells XE, Lees EM
  Title
Ureidoglycolate amidohydrolase from developing French bean fruits (Phaseolus vulgaris [L.].).
  Journal
Arch. Biochem. Biophys. 287 (1991) 151-9.
Reference
3  [PMID:19935661]
  Authors
Werner AK, Romeis T, Witte CP
  Title
Ureide catabolism in Arabidopsis thaliana and Escherichia coli.
  Journal
Nat. Chem. Biol. 6 (2010) 19-21.
  Sequence
[ath:AT5G43600]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
115629-07-7

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