KEGG   ENZYME: 3.5.1.12Help
Entry
EC 3.5.1.12                 Enzyme                                 

Name
biotinidase;
amidohydrolase biotinidase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
biotin-amide amidohydrolase
Reaction(IUBMB)
biotin amide + H2O = biotin + NH3 [RN:R01076]
Reaction(KEGG)
R01076;
(other) R01077 R06134
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Substrate
biotin amide [CPD:C01893];
H2O [CPD:C00001]
Product
biotin [CPD:C00120];
NH3 [CPD:C00014]
Comment
Also acts on biotin esters.
Pathway
Biotin metabolism
Metabolic pathways
Orthology
K01435  
biotinidase
Genes
HSA: 
686(BTD)
PTR: 
470760(BTD)
PPS: 
GGO: 
PON: 
MCC: 
677722(BTD)
MCF: 
MMU: 
26363(Btd)
RNO: 
306262(Btd)
CGE: 
HGL: 
TUP: 
CFA: 
477059(BTD)
AML: 
FCA: 
BTA: 
537669(BTD)
BOM: 
PHD: 
CHX: 
SSC: 
CFR: 
ECB: 
MYB: 
MDO: 
SHR: 
OAA: 
GGA: 
420639(BTD)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FPG: 
FCH: 
CLV: 
ASN: 
PSS: 
ACS: 
XTR: 
DRE: 
555376(btd)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
DME: 
Dmel_CG32754(vanin-like)
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
API: 
 » show all
Taxonomy
Reference
1  [PMID:14087327]
  Authors
KNAPPE J, BRUEMMER W, BIEDERBICK K.
  Title
[PURIFICATION AND PROPERTIES OF BIOTINIDASE FROM SWINE KIDNEY AND LACTOBACILLUS CASEI.]
  Journal
Biochem. Z. 338 (1963) 599-613.
  Organism
Lactobacillus casei
Reference
2  [PMID:13211594]
  Authors
THOMA RW, PETERSON WH.
  Title
The enzymatic degradation of soluble bound biotin.
  Journal
J. Biol. Chem. 210 (1954) 569-79.
  Organism
Sus scofa [GN:ssc]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9025-15-4

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