KEGG   ENZYME: 3.5.1.6Help
Entry
EC 3.5.1.6                  Enzyme                                 

Name
beta-ureidopropionase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N-carbamoyl-beta-alanine amidohydrolase
Reaction(IUBMB)
N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3 [RN:R00905]
Reaction(KEGG)
Substrate
N-carbamoyl-beta-alanine [CPD:C02642];
H2O [CPD:C00001]
Product
beta-alanine [CPD:C00099];
CO2 [CPD:C00011];
NH3 [CPD:C00014]
Comment
The animal enzyme also acts on beta-ureidoisobutyrate.
History
EC 3.5.1.6 created 1961
Pathway
Pyrimidine metabolism
beta-Alanine metabolism
Pantothenate and CoA biosynthesis
Drug metabolism - other enzymes
Metabolic pathways
Orthology
K01431  
beta-ureidopropionase
Genes
HSA: 
51733(UPB1)
PTR: 
747532(UPB1)
PPS: 
100970346(UPB1)
GGO: 
101124006(UPB1)
PON: 
100172385(UPB1)
MCC: 
707752(UPB1)
MCF: 
102131737(UPB1)
MMU: 
103149(Upb1)
RNO: 
116593(Upb1)
CGE: 
100762944(Upb1)
HGL: 
101718416(Upb1)
TUP: 
102489145(UPB1)
CFA: 
486398(UPB1)
AML: 
100478175(UPB1)
FCA: 
101081004(UPB1)
PTG: 
102958013(UPB1)
BTA: 
504557(UPB1)
BOM: 
102274215(UPB1)
PHD: 
102343106(UPB1)
CHX: 
102183534(UPB1)
OAS: 
101119507(UPB1)
SSC: 
100155919(UPB1)
CFR: 
102520732(UPB1)
BACU: 
103007663(UPB1)
LVE: 
103076427(UPB1)
ECB: 
100053177(UPB1)
MYB: 
102241225(UPB1)
MYD: 
102774490(UPB1)
PALE: 
102896931(UPB1)
MDO: 
100013001(UPB1)
SHR: 
OAA: 
100084610(UPB1)
GGA: 
416949(UPB1)
MGP: 
APLA: 
101805137(UPB1)
TGU: 
100224765(UPB1)
FAB: 
101811213(UPB1)
PHI: 
102100917(UPB1)
FPG: 
101910283(UPB1)
FCH: 
102052174(UPB1)
CLV: 
102094038(UPB1)
ASN: 
102380155(UPB1)
AMJ: 
102570812(UPB1)
PSS: 
102461367(UPB1)
CMY: 
102930361(UPB1)
ACS: 
100554981(upb1)
PBI: 
103054266(UPB1)
XLA: 
447326(upb1)
XTR: 
100145317(upb1)
DRE: 
322660(upb1)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
102347123(UPB1)
CMK: 
103183972(upb1)
BFO: 
CIN: 
100187207(upb1)
SPU: 
DME: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
409250(GB20148)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
NVE: 
HMG: 
TAD: 
AQU: 
ATH: 
AT5G64370(BETA-UP)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
MTR: 
CAM: 
FVE: 
PPER: 
PMUM: 
MDM: 
CSV: 
CMO: 
RCU: 
POP: 
POPTR_0007s03190g(POPTRDRAFT_819740)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os07t0485100-01(Os07g0485100)
OBR: 
BDI: 
SBI: 
SORBI_02g033430(SORBIDRAFT_02g033430)
ZMA: 
100283449(bas1)
SITA: 
ATR: 
s00033p00236370(AMTR_s00033p00236370)
SMO: 
PPP: 
CRE: 
VCN: 
MIS: 
CVR: 
CGR: 
PIC: 
DDI: 
DPP: 
DFA: 
DFA_06459(pyd3)
ACAN: 
NGR: 
 » show all
Taxonomy
Reference
1  [PMID:13849303]
  Authors
CAMPBELL LL.
  Title
Reductive degradation of pyrimidines. 5. Enzymatic conversion of N-carbamyl-beta-alanine to beta-alanine, carbon dioxide, and ammonia.
  Journal
J. Biol. Chem. 235 (1960) 2375-8.
Reference
2  [PMID:13538975]
  Authors
CARAVACA J, GRISOLIA S.
  Title
Enzymatic decarbamylation of carbamyl beta-alanine and carbamyl beta-aminoisobutyric acid.
  Journal
J. Biol. Chem. 231 (1958) 357-65.
Reference
3  [PMID:6433973]
  Authors
Traut TW, Loechel S.
  Title
Pyrimidine catabolism: individual characterization of the three sequential enzymes with a new assay.
  Journal
Biochemistry. 23 (1984) 2533-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9027-27-4

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