KEGG   ENZYME: 3.5.1.76Help
Entry
EC 3.5.1.76                 Enzyme                                 

Name
arylalkyl acylamidase;
aralkyl acylamidase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides
BRITE hierarchy
Sysname
N-acetylarylalkylamine amidohydrolase
Reaction(IUBMB)
N-acetylarylalkylamine + H2O = arylalkylamine + acetate [RN:R04727]
Reaction(KEGG)
Substrate
N-acetylarylalkylamine [CPD:C02998];
H2O [CPD:C00001]
Product
arylalkylamine [CPD:C01890];
acetate [CPD:C00033]
Comment
Identified in Pseudomonas putida. Strict specificity for N-acetyl arylalkylamines, including N-acetyl-2-phenylethylamine, N-acetyl-3-phenylpropylamine, N-acetyldopamine, N-acetyl-serotonin and melatonin. It also accepts arylalkyl acetates but not acetanilide derivatives, which are common substrates of EC 3.5.1.13, aryl acylamidase.
History
EC 3.5.1.76 created 1999
Reference
1  [PMID:1396711]
  Authors
Shimizu S, Ogawa J, Chung MC, Yamada H.
  Title
Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2.
  Journal
Eur. J. Biochem. 209 (1992) 375-82.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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