KEGG   ENZYME: 3.5.2.12Help
Entry
EC 3.5.2.12                 Enzyme                                 

Name
6-aminohexanoate-cyclic-dimer hydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amides
BRITE hierarchy
Sysname
1,8-diazacyclotetradecane-2,9-dione lactamhydrolase
Reaction(IUBMB)
1,8-diazacyclotetradecane-2,9-dione + H2O = N-(6-aminohexanoyl)-6-aminohexanoate [RN:R03448]
Reaction(KEGG)
Substrate
1,8-diazacyclotetradecane-2,9-dione [CPD:C04277];
H2O [CPD:C00001]
Product
N-(6-aminohexanoyl)-6-aminohexanoate [CPD:C01255]
Comment
The cyclic dimer of 6-aminohexanoate is converted to the linear dimer.
History
EC 3.5.2.12 created 1983
Pathway
Caprolactam degradation
Microbial metabolism in diverse environments
Orthology
K01471  
6-aminohexanoate-cyclic-dimer hydrolase
Reference
1  [PMID:923591]
  Authors
Kinoshita S, Negoro S, Muramatsu M, Bisaria VS, Sawada S, Okada H.
  Title
6-Aminohexanoic acid cyclic dimer hydrolase. A new cyclic amide hydrolase produced by Achromobacter guttatus KI74.
  Journal
Eur. J. Biochem. 80 (1977) 489-95.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
60976-29-6

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