KEGG   ENZYME: 3.5.2.13Help
Entry
EC 3.5.2.13                 Enzyme                                 

Name
2,5-dioxopiperazine hydrolase;
cyclo(Gly-Gly) hydrolase;
cyclo(glycylglycine) hydrolase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amides
BRITE hierarchy
Sysname
2,5-dioxopiperazine amidohydrolase
Reaction(IUBMB)
2,5-dioxopiperazine + H2O = glycylglycine [RN:R03810]
Reaction(KEGG)
Substrate
2,5-dioxopiperazine [CPD:C02777];
H2O [CPD:C00001]
Product
glycylglycine [CPD:C02037]
Comment
Highly specific; does not hydrolyse other dioxopiperazines, glycylglycine, proteins or barbiturates.
History
EC 3.5.2.13 created 1989
Reference
1
  Authors
Suzuki, Y. and Uchida, K.
  Title
Multiple forms of alpha-glycosidase from pig duodenum.
  Journal
Agric. Biol. Chem. 49 (1985) 1573-1581.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
97599-45-6

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