KEGG   ENZYME: 3.5.3.2Help
Entry
EC 3.5.3.2                  Enzyme                                 

Name
guanidinoacetase;
glycocyaminase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amidines
BRITE hierarchy
Sysname
guanidinoacetate amidinohydrolase
Reaction(IUBMB)
guanidinoacetate + H2O = glycine + urea [RN:R00775]
Reaction(KEGG)
Substrate
guanidinoacetate [CPD:C00581];
H2O [CPD:C00001]
Product
glycine [CPD:C00037];
urea [CPD:C00086]
Comment
Requires Mn2+.
History
EC 3.5.3.2 created 1961
Reference
1  [PMID:14791411]
  Authors
ROCHE J, LACOMBE G, GIRARD H.
  Title
[On the specificity of certain bacterial deguanidases generating urea and on arginindihydrolase.]
  Journal
Biochim. Biophys. Acta. 6 (1950) 210-6.
Reference
2
  Authors
Yorifuji, T., Tamai, H. and Usami, H.
  Title
Purification, crystallization and properties of Mn2+ dependent guanidoacetate amidinohydrolase from a Pseudomonas.
  Journal
Agric. Biol. Chem. 41 (1977) 959-966.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9024-92-4

DBGET integrated database retrieval system