Entry
Name
adenosine-phosphate deaminase;
adenylate deaminase;
adenine nucleotide deaminase;
adenosine (phosphate) deaminase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
BRITE hierarchy
Sysname
adenosine-phosphate aminohydrolase
Reaction(IUBMB)
(1) AMP + H2O = IMP + NH3 [RN:
R00181 ];
(2) ADP + H2O = IDP + NH3 [RN:
R00123 ];
(3) ATP + H2O = ITP + NH3 [RN:
R00088 ]
Reaction(KEGG)
Substrate
Product
Comment
Acts on AMP, ADP, ATP, NAD+ and adenosine, in decreasing order of activity. The bacterial enzyme can also accept the deoxy derivatives. cf. EC
3.5.4.6 , AMP deaminase.
History
EC 3.5.4.17 created 1972, modified 1980, modified 2014
Reference
Authors
Su JC, Li CC, Ting CC.
Title
A new adenylate deaminase from red marine alga Porphyra crispata.
Journal
Reference
Authors
Yates MG.
Title
A non-specific adenine nucleotide deaminase from desulfovibrio desulfuricans.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 3.5.4.17
ExPASy - ENZYME nomenclature database: 3.5.4.17