KEGG   ENZYME: 3.5.4.17Help
Entry
EC 3.5.4.17                 Enzyme                                 

Name
adenosine-phosphate deaminase;
adenylate deaminase;
adenine nucleotide deaminase;
adenosine (phosphate) deaminase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
BRITE hierarchy
Sysname
adenosine-phosphate aminohydrolase
Reaction(IUBMB)
AMP + H2O = IMP + NH3 [RN:R00181]
Reaction(KEGG)
Substrate
AMP [CPD:C00020];
H2O [CPD:C00001]
Product
IMP [CPD:C00130];
NH3 [CPD:C00014]
Comment
Acts on AMP, ADP, ATP, NAD+ and adenosine, in decreasing order of activity. The bacterial enzyme also acts on the deoxy derivatives. cf. EC 3.5.4.6, AMP deaminase.
History
EC 3.5.4.17 created 1972, modified 1980
Reference
1  [PMID:5940938]
  Authors
Su JC, Li CC, Ting CC.
  Title
A new adenylate deaminase from red marine alga Porphyra crispata.
  Journal
Biochemistry. 5 (1966) 536-43.
  Organism
Porphyra crispata
Reference
2  [PMID:5773435]
  Authors
Yates MG.
  Title
A non-specific adenine nucleotide deaminase from desulfovibrio desulfuricans.
  Journal
Biochim. Biophys. Acta. 171 (1969) 299-310.
  Organism
Desulfovibrio desulfuricans
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37289-20-6

DBGET integrated database retrieval system