KEGG   ENZYME: 3.5.4.23Help
Entry
EC 3.5.4.23                 Enzyme                                 
Name
blasticidin-S deaminase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In cyclic amidines
BRITE hierarchy
Sysname
blasticidin-S aminohydrolase
Reaction(IUBMB)
blasticidin S + H2O = deaminohydroxyblasticidin S + NH3 [RN:R03800]
Reaction(KEGG)
R03800;
(other) R06137
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Substrate
blasticidin S [CPD:C02010];
H2O [CPD:C00001]
Product
deaminohydroxyblasticidin S [CPD:C03860];
NH3 [CPD:C00014]
Comment
Catalyses the deamination of the cytosine moiety of the antibiotics blasticidin S, cytomycin and acetylblasticidin S.
Orthology
K06017  
Genes
GBE: 
BCZ: 
BTL: 
Taxonomy
Reference
1  [PMID:236272]
  Authors
Yamaguchi I, Shibata H, Seto H, Misato T.
  Title
Isolation and purification of blasticidin S deaminase from Aspergillus terreus.
  Journal
J. Antibiot. (Tokyo). 28 (1975) 7-14.
  Organism
Aspergillus terreus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
54576-55-5
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