KEGG   ENZYME: 3.5.5.4Help
Entry
EC 3.5.5.4                  Enzyme                                 

Name
cyanoalanine nitrilase;
beta-cyanoalanine nitrilase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
BRITE hierarchy
Sysname
3-cyano-L-alanine aminohydrolase
Reaction(IUBMB)
3-cyano-L-alanine + 2 H2O = L-aspartate + NH3 (overall reaction) [RN:R00486];
(1a) 3-cyano-L-alanine + H2O = L-asparagine [RN:R01267];
(1b) L-asparagine + H2O = L-aspartate + NH3 [RN:R00485]
Reaction(KEGG)
Substrate
3-cyano-L-alanine [CPD:C02512];
H2O [CPD:C00001];
L-asparagine [CPD:C00152]
Product
L-aspartate [CPD:C00049];
NH3 [CPD:C00014];
L-asparagine [CPD:C00152]
Comment
L-Asparagine is formed as an intermediate. cf. EC 4.2.1.65, 3-cyanoalanine hydratase and EC 3.5.1.1, asparaginase.
History
EC 3.5.5.4 created 1986
Pathway
Cyanoamino acid metabolism
Orthology
K13035  
beta-cyano-L-alanine hydratase/nitrilase
Genes
ATH: 
AT5G22300(NIT4)
ALY: 
CRB: 
EUS: 
CIT: 
CIC: 
TCC: 
GMX: 
PVU: 
CAM: 
FVE: 
PPER: 
CSV: 
RCU: 
POP: 
POPTR_0004s20980g POPTR_0006s22420g(POPTRDRAFT_417421) POPTR_0009s16260g(POPTRDRAFT_199891) POPTR_0016s07510g(POPTRDRAFT_835475)
VVI: 
SLY: 
SOT: 
OSA: 
DOSA: 
Os02t0635200-01(Os02g0635200)
OBR: 
BDI: 
SBI: 
SORBI_04g026950(SORBIDRAFT_04g026950) SORBI_06g023120(SORBIDRAFT_06g023120)
ZMA: 
542093(NIT2)
SITA: 
ATR: 
s00030p00245780(AMTR_s00030p00245780) s00030p00246840(AMTR_s00030p00246840) s00114p00148330(AMTR_s00114p00148330)
SMO: 
PPP: 
DSQ: 
PCO: 
PSQ: 
MRR: 
SLA: 
 » show all
Taxonomy
Reference
1
  Authors
Yanase, H., Sakai, T. and Tonomuro, K.
  Title
Purification, crystallization and some properties of beta-cyano-L-alanine-degrading enzyme in Pseudomonas sp. 13.
  Journal
Agric. Biol. Chem. 47 (1983) 473-482.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
85638-44-4

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