KEGG   ENZYME: 3.5.5.6Help
Entry
EC 3.5.5.6                  Enzyme                                 

Name
bromoxynil nitrilase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
BRITE hierarchy
Sysname
3,5-dibromo-4-hydroxybenzonitrile aminohydrolase
Reaction(IUBMB)
3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH3 [RN:R04349]
Reaction(KEGG)
Substrate
3,5-dibromo-4-hydroxybenzonitrile [CPD:C04178];
H2O [CPD:C00001]
Product
3,5-dibromo-4-hydroxybenzoate [CPD:C03925];
NH3 [CPD:C00014]
Comment
Involved in the bacterial degradation of the herbicide bromoxynil. Highly specific.
History
EC 3.5.5.6 created 1992
Pathway
Fluorobenzoate degradation
Microbial metabolism in diverse environments
Orthology
K20806  
bromoxynil nitrilase
Genes
SVI: 
Taxonomy
Reference
1  [PMID:2834373]
  Authors
Stalker DM, Malyj LD, McBride KE.
  Title
Purification and properties of a nitrilase specific for the herbicide bromoxynil and corresponding nucleotide sequence analysis of the bxn gene.
  Journal
J. Biol. Chem. 263 (1988) 6310-4.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
157857-12-0

DBGET integrated database retrieval system