KEGG   ENZYME: 3.5.5.6Help
Entry
EC 3.5.5.6                  Enzyme                                 

Name
bromoxynil nitrilase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
BRITE hierarchy
Sysname
3,5-dibromo-4-hydroxybenzonitrile aminohydrolase
Reaction(IUBMB)
3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH3 [RN:R04349]
Reaction(KEGG)
Substrate
3,5-dibromo-4-hydroxybenzonitrile [CPD:C04178];
H2O [CPD:C00001]
Product
3,5-dibromo-4-hydroxybenzoate [CPD:C03925];
NH3 [CPD:C00014]
Comment
Involved in the bacterial degradation of the herbicide bromoxynil. Highly specific.
History
EC 3.5.5.6 created 1992
Pathway
Fluorobenzoate degradation
Microbial metabolism in diverse environments
Reference
1  [PMID:2834373]
  Authors
Stalker DM, Malyj LD, McBride KE.
  Title
Purification and properties of a nitrilase specific for the herbicide bromoxynil and corresponding nucleotide sequence analysis of the bxn gene.
  Journal
J. Biol. Chem. 263 (1988) 6310-4.
  Sequence
[up:P10045]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
157857-12-0

DBGET integrated database retrieval system