| Entry |
|
|---|
| Name |
thiocyanate hydrolase |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
 |
|---|
| Sysname |
thiocyanate aminohydrolase |
|---|
| Reaction(IUBMB) |
thiocyanate + 2 H2O = carbonyl sulfide + NH3 + HO- [RN:R05780] |
|---|
| Reaction(KEGG) |
R05780
 |
|---|
| Substrate |
thiocyanate [CPD:C01755];
H2O [CPD:C00001] |
|---|
| Product |
carbonyl sulfide [CPD:C07331];
NH3 [CPD:C00014];
HO- [CPD:C01328] |
|---|
| Comment |
The enzyme from Thiobacillus thioparus catalyses the first step in
the degradation of thiocyanate. |
|---|
| Structures |
PDB: 2DD4 2DD5 2DXB 2DXC 2ZZD |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:9573140]
Katayama Y, Matsushita Y, Kaneko M, Kondo M, Mizuno T, Nyunoya H.
Cloning of genes coding for the three subunits of thiocyanate
hydrolase of Thiobacillus thioparus THI 115 and their evolutionary
relationships to nitrile hydratase.
J. Bacteriol. 180 (1998) 2583-9.
Thiobacillus thioparus |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:1577754]
Katayama Y, Narahara Y, Inoue Y, Amano F, Kanagawa T, Kuraishi H.
A thiocyanate hydrolase of Thiobacillus thioparus. A novel enzyme
catalyzing the formation of carbonyl sulfide from thiocyanate.
J. Biol. Chem. 267 (1992) 9170-5.
Thiobacillus thioparus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.5.8
IUBMB Enzyme Nomenclature: 3.5.5.8
ExPASy - ENZYME nomenclature database: 3.5.5.8
UM-BBD (Biocatalysis/Biodegradation Database): 3.5.5.8
BRENDA, the Enzyme Database: 3.5.5.8
CAS: 142539-65-9 |
|---|
