| Entry |
|
| Name |
thiocyanate hydrolase |
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
 |
| Sysname |
thiocyanate aminohydrolase |
| Reaction(IUBMB) |
thiocyanate + 2 H2O = carbonyl sulfide + NH3 + HO- [RN:R05780] |
| Reaction(KEGG) |
R05780
 |
| Substrate |
thiocyanate [CPD:C01755];
H2O [CPD:C00001] |
| Product |
carbonyl sulfide [CPD:C07331];
NH3 [CPD:C00014];
HO- [CPD:C01328] |
| Comment |
The enzyme from Thiobacillus thioparus catalyses the first step in
the degradation of thiocyanate. |
| Structures |
PDB: 2DD4 2DD5 2DXB 2DXC 2ZZD |
Reference Authors Title
Journal Organism
|
1 [PMID:9573140]
Katayama Y, Matsushita Y, Kaneko M, Kondo M, Mizuno T, Nyunoya H.
Cloning of genes coding for the three subunits of thiocyanate
hydrolase of Thiobacillus thioparus THI 115 and their evolutionary
relationships to nitrile hydratase.
J. Bacteriol. 180 (1998) 2583-9.
Thiobacillus thioparus |
Reference Authors Title
Journal Organism
|
2 [PMID:1577754]
Katayama Y, Narahara Y, Inoue Y, Amano F, Kanagawa T, Kuraishi H.
A thiocyanate hydrolase of Thiobacillus thioparus. A novel enzyme
catalyzing the formation of carbonyl sulfide from thiocyanate.
J. Biol. Chem. 267 (1992) 9170-5.
Thiobacillus thioparus |
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.5.8
IUBMB Enzyme Nomenclature: 3.5.5.8
ExPASy - ENZYME nomenclature database: 3.5.5.8
UM-BBD (Biocatalysis/Biodegradation Database): 3.5.5.8
BRENDA, the Enzyme Database: 3.5.5.8
CAS: 142539-65-9 |