| Entry |
|
|---|
| Name |
N-isopropylammelide isopropylaminohydrolase;
AtzC |
|---|
| Class |
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In other compounds
 |
|---|
| Sysname |
N-isopropylammelide isopropylaminohydrolase |
|---|
| Reaction(IUBMB) |
N-isopropylammelide + H2O = cyanuric acid + isopropylamine
[RN:R05560] |
|---|
| Reaction(KEGG) |
R05560;
(other) R06967
 |
|---|
| Substrate |
N-isopropylammelide [CPD:C06553];
H2O [CPD:C00001] |
|---|
| Product |
cyanuric acid [CPD:C06554];
isopropylamine [CPD:C06748] |
|---|
| Comment |
Involved in a pathway by which the herbicide atrazine,
2-chloro-4-(ethylamino)-6-(isopopylamino)-1,3,5-triazine, is
degraded in bacteria via N-isopropylammelide,
2,4-dihydroxy-6-(isopropylamino)-1,3,5-triazine. |
|---|
| Pathway |
PATH: ec00791 Atrazine degradation
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K08710 N-isopropylammelide isopropylaminohydrolase |
|---|
| Genes |
BXE: Bxe_A2120
VEI: Veis_0416
PDE: Pden_1057
ART: Arth_3600
NCA: Noca_1495
 |
|---|
| Structures |
PDB: 2QT3 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:9422605]
Sadowsky MJ, Tong Z, de Souza M, Wackett LP.
AtzC is a new member of the amidohydrolase protein superfamily and
is homologous to other atrazine-metabolizing enzymes.
J. Bacteriol. 180 (1998) 152-8.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.5.99.4
IUBMB Enzyme Nomenclature: 3.5.99.4
ExPASy - ENZYME nomenclature database: 3.5.99.4
UM-BBD (Biocatalysis/Biodegradation Database): 3.5.99.4
BRENDA, the Enzyme Database: 3.5.99.4
CAS: 203810-02-0 |
|---|
