KEGG   ENZYME: 3.6.1.12Help
Entry
EC 3.6.1.12                 Enzyme                                 

Name
dCTP diphosphatase;
deoxycytidine-triphosphatase;
dCTPase;
dCTP pyrophosphatase;
deoxycytidine triphosphatase;
deoxy-CTPase;
dCTPase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
BRITE hierarchy
Sysname
dCTP nucleotidohydrolase
Reaction(IUBMB)
dCTP + H2O = dCMP + diphosphate [RN:R01668]
Reaction(KEGG)
R01668;
(other) R01667
Show
Substrate
dCTP [CPD:C00458];
H2O [CPD:C00001]
Product
dCMP [CPD:C00239];
diphosphate [CPD:C00013]
Comment
Also hydrolyses dCDP to dCMP and phosphate.
History
EC 3.6.1.12 created 1965
Pathway
Pyrimidine metabolism
Metabolic pathways
Orthology
K16904  
dCTP diphosphatase
Genes
HSA: 
79077(DCTPP1)
PTR: 
467948(DCTPP1)
PPS: 
100980571(DCTPP1)
GGO: 
101138322(DCTPP1)
NLE: 
100584469(DCTPP1)
MCC: 
710500(DCTPP1)
MCF: 
102118443(DCTPP1)
CSAB: 
103230924(DCTPP1)
RRO: 
104681570(DCTPP1)
CJC: 
100408453(DCTPP1)
SBQ: 
101051189(DCTPP1)
MMU: 
66422(Dctpp1)
RNO: 
192252(Dctpp1)
CGE: 
100769832(Dctpp1)
NGI: 
103726355(Dctpp1)
OCU: 
100357182(DCTPP1)
TUP: 
102469976(DCTPP1)
CFA: 
489903(DCTPP1)
AML: 
100479684(DCTPP1)
UMR: 
103657859(DCTPP1)
FCA: 
101094313(DCTPP1)
PTG: 
102950940(DCTPP1)
BTA: 
614103(DCTPP1)
BOM: 
102282512(DCTPP1)
PHD: 
102342910(DCTPP1)
CHX: 
102171294(DCTPP1)
OAS: 
101121995(DCTPP1)
SSC: 
100621901(DCTPP1)
CFR: 
102520187(DCTPP1)
BACU: 
103015138(DCTPP1)
LVE: 
103086998(DCTPP1)
ECB: 
100065556(DCTPP1)
MYB: 
MYD: 
102753729(DCTPP1)
PALE: 
102878907(DCTPP1)
LAV: 
104846757(DCTPP1)
MDO: 
100017749(DCTPP1)
SHR: 
100932588(DCTPP1)
OAA: 
100093573(DCTPP1)
ACS: 
100558769(dctpp1)
PBI: 
103056195(DCTPP1)
GJA: 
107106259(DCTPP1)
XLA: 
444233(dctpp1)
XTR: 
493314(dctpp1)
DRE: 
393744(dctpp1)
TRU: 
101062264(dctpp1)
TNG: 
MZE: 
101486589(dctpp1)
OLA: 
101157671(dctpp1)
XMA: 
102238234(dctpp1)
SASA: 
100196870(xtp3a)
LCM: 
102360709(DCTPP1)
BFO: 
SPU: 
SKO: 
ISC: 
LGI: 
CRG: 
OBI: 
ADF: 
AQU: 
ALY: 
CRB: 
EUS: 
BRP: 
BNA: 
THJ: 
CIT: 
CIC: 
TCC: 
GRA: 
EGR: 
GMX: 
PVU: 
VRA: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj0g3v0107379.1(Lj0g3v0107379.1) Lj4g3v1683160.1(Lj4g3v1683160.1)
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
CSV: 
CMO: 
RCU: 
JCU: 
POP: 
POPTR_0002s23610g(POPTRDRAFT_553082) POPTR_0002s25150g(POPTRDRAFT_709767) POPTR_0014s14550g(POPTRDRAFT_1099619)
VVI: 
SLY: 
SPEN: 
SOT: 
SIND: 
BVG: 
NNU: 
OSA: 
4329363(P0519B12.2)
DOSA: 
Os02t0479300-01(Os02g0479300) Os04t0346800-01(Os04g0346800)
OBR: 
BDI: 
SBI: 
SORBI_04g019220(SORBIDRAFT_04g019220)
ZMA: 
100282064(GRMZM2G077989) 100284231
SITA: 
PDA: 
EGU: 
MUS: 
ATR: 
SMO: 
PPP: 
VCN: 
MIS: 
CVR: 
TET: 
PTM: 
AAF: 
SPAR: 
EHX: 
GTT: 
NGR: 
 » show all
Taxonomy
Reference
1  [PMID:13788541]
  Authors
ZIMMERMAN SB, KORNBERG A.
  Title
Deoxycytidine di- and triphosphate cleavage by an enzyme formed in bacteriophage-infected Eschrichia coli.
  Journal
J. Biol. Chem. 236 (1961) 1480-6.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9024-87-7

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