KEGG   ENZYME: 3.6.1.21Help
Entry
EC 3.6.1.21                 Enzyme                                 

Name
ADP-sugar diphosphatase;
ADP-sugar pyrophosphatase;
adenosine diphosphosugar pyrophosphatase
Class
Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides
BRITE hierarchy
Sysname
ADP-sugar sugarphosphohydrolase
Reaction(IUBMB)
ADP-sugar + H2O = AMP + alpha-D-aldose 1-phosphate [RN:R03570]
Reaction(KEGG)
Substrate
ADP-sugar [CPD:C01469];
H2O [CPD:C00001]
Product
AMP [CPD:C00020];
alpha-D-aldose 1-phosphate [CPD:C00991]
Comment
Has a specificity that is distinct from that of UDP-sugar diphosphatase (EC 3.6.1.45).
History
EC 3.6.1.21 created 1972, modified 1999
Pathway
Fructose and mannose metabolism
Purine metabolism
Starch and sucrose metabolism
Reference
1  [PMID:5686292]
  Authors
Rodriguez P, Bass ST, Hansen RG.
  Title
A pyrophosphatase from mammalian tissues specific for derivatives of ADP.
  Journal
Biochim. Biophys. Acta. 167 (1968) 199-201.
  Organism
cow, Rattus norvegicus, Oryctolagus cuniculus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37289-32-0

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