KEGG   ENZYME: 3.6.2.2Help
Entry
EC 3.6.2.2                  Enzyme                                 

Name
phosphoadenylylsulfatase;
3-phosphoadenylyl sulfatase;
3-phosphoadenosine 5-phosphosulfate sulfatase;
PAPS sulfatase;
3'-phosphoadenylylsulfate sulfohydrolase
Class
Hydrolases;
Acting on acid anhydrides;
In sulfonyl-containing anhydrides
BRITE hierarchy
Sysname
3'-phosphoadenylyl-sulfate sulfohydrolase
Reaction(IUBMB)
3'-phosphoadenylyl sulfate + H2O = adenosine 3',5'-bisphosphate + sulfate [RN:R00507]
Reaction(KEGG)
Substrate
3'-phosphoadenylyl sulfate [CPD:C00053];
H2O [CPD:C00001]
Product
adenosine 3',5'-bisphosphate [CPD:C00054];
sulfate [CPD:C00059]
Comment
Requires Mn2+.
History
EC 3.6.2.2 created 1972
Pathway
Purine metabolism
Sulfur metabolism
Reference
1  [PMID:13864264]
  Authors
BALASUBRAMANIAN AS, BACHHAWAT BK.
  Title
Enzymic degradation of active sulphate.
  Journal
Biochim. Biophys. Acta. 59 (1962) 389-97.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37289-37-5

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