KEGG   ENZYME: 3.6.3.1Help
Entry
EC 3.6.3.1                  Enzyme                                 

Name
phospholipid-translocating ATPase;
Mg2+-ATPase;
flippase;
aminophospholipid-transporting ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances
BRITE hierarchy
Sysname
ATP phosphohydrolase (phospholipid-flipping)
Reaction(IUBMB)
ATP + H2O + phospholipid[side 1] = ADP + phosphate + phospholipid[side 2] [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
phospholipid[side 1]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
phospholipid[side 2]
Comment
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. The enzyme moves phospholipids such as phosphatidylcholine, phosphatidylserine, and phosphatidylethanolamine from one membrane face to the other ('flippase').
History
EC 3.6.3.1 created 2000 (EC 3.6.3.13 created 2000, incorporated 2001)
Orthology
K01530  
phospholipid-translocating ATPase
K14802  
phospholipid-transporting ATPase
Genes
HSA: 
10079(ATP9A) 10396(ATP8A1) 148229(ATP8B3) 23120(ATP10B) 23200(ATP11B) 23250(ATP11A) 286410(ATP11C) 374868(ATP9B) 51761(ATP8A2) 5205(ATP8B1) 57194(ATP10A) 57198(ATP8B2) 57205(ATP10D) 79895(ATP8B4)
PTR: 
452677(ATP11A) 453268(ATP10A) 453422(ATP8B4) 455439(ATP8B1) 455484(ATP9B) 458341(ATP9A) 461189(ATP8A1) 461351(ATP10D) 462239(ATP10B) 465889(ATP11C) 467238(ATP8A2) 468652(ATP8B3) 469505(ATP8B2) 471016(ATP11B)
PPS: 
100967766(ATP8B4) 100969989 100972951(ATP8B2) 100973832(ATP8B1) 100975459(ATP8B3) 100977504(ATP10B) 100977979(ATP10A) 100978328(ATP9B) 100979452 100979822(ATP10D) 100981064(ATP9A) 100985769(ATP11A) 100986009(ATP8A2) 100989463(ATP8A1) 100994939(ATP11B) 100995604(ATP11C)
GGO: 
101126969(ATP8A1) 101127464(ATP8A2) 101129100(ATP8B2) 101130545(ATP11C) 101130730(ATP8B4) 101133046(ATP8B3) 101133383(ATP10A) 101135145(ATP11A) 101136146(ATP9A) 101138062(ATP10D) 101139526(ATP11B) 101142420 101142751(ATP8B1) 101147224(ATP9B) 101149030(ATP10B)
PON: 
100171619(ATP8B4) 100435833(ATP9B) 100440505(ATP10A) 100441755(ATP8B3) 100443731(ATP10B) 100446108 100446310 100446676(ATP8A1) 100448675(ATP11C) 100450195(ATP8B1) 100450527(ATP11A) 100451934(ATP9A) 100453547(ATP10D) 100460078(ATP8B2) 100461085(ATP11B)
NLE: 
100582757(ATP8A2) 100582836(ATP8B4) 100583287(ATP10B) 100586561(ATP10A) 100588834(ATP8B1) 100592609(ATP8A1) 100595005(ATP10D) 100598430(ATP9B) 100599296(ATP11B) 100600857(ATP11C) 100602175 100603161(ATP11A) 100604358(ATP9A) 100604398(ATP8B3) 100605947(ATP8B2)
MCC: 
695802(ATP11C) 695994(ATP8B1) 697274 697957(ATP9B) 698170(ATP10B) 702630(ATP8A1) 704458(ATP10D) 708453(ATP11B) 709311(ATP8A2) 710250(ATP9A) 711435(ATP10A) 712589(ATP11A) 716570(ATP8B4) 716652(ATP8B2) 721348(ATP8B3)
MCF: 
101866259 101925402(ATP11B) 102114806(ATP11A) 102116390(ATP11C) 102118254(ATP8B2) 102127028(ATP10A) 102127268(ATP10D) 102132865(ATP8B3) 102135092(ATP10B) 102137184(ATP9B) 102138350(ATP8B1) 102138535(ATP8B4) 102139473(ATP9A) 102145170(ATP8A1) 102145479(ATP8A2)
CSAB: 
103214821(ATP11A) 103219230 103221172(ATP11B) 103223926(ATP8B2) 103232668(ATP11C) 103233618(ATP8B3) 103244032(ATP9B) 103244203(ATP9A) 103244219(ATP8B1) 103244911(ATP10B) 103245654(ATP8B4) 103246016(ATP10A) 103246141(ATP10D) 103246160(ATP8A1) 103249035(ATP8A2)
RRO: 
104655723(ATP9B) 104656535 104656542(ATP10A) 104656911(ATP8B4) 104659538(ATP10D) 104659912(ATP11A) 104659980(ATP8A2) 104662366(ATP9A) 104662686(ATP8A1) 104663494(ATP8B2) 104664655(ATP11B) 104667796 104669349 104671251(ATP8B1) 104671406(ATP8B3) 104672372 104672653 104682198(ATP11C) 104682298(ATP10B)
RBB: 
108512908 108515307 108519006 108521040(ATP11B) 108521824(ATP11A) 108523656 108525050(ATP9B) 108526612(ATP8B2) 108528502(ATP8A1) 108529705(ATP11C) 108530023(ATP10D) 108530229(ATP8B3) 108535940(ATP10A) 108537953(ATP10B) 108539457(ATP9A) 108541040(ATP8B1)
CJC: 
100384935(ATP8B2) 100386296(ATP8A2) 100387255(ATP10A) 100398880(ATP8B1) 100399705(ATP8B4) 100401800(ATP9B) 100402529 100402929(ATP8B3) 100403060(ATP11C) 100404856(ATP8A1) 100407984(ATP10B) 100409661(ATP11A) 100409912(ATP11B) 100413995(ATP10D) 100415211(ATP9A)
SBQ: 
101027844(ATP10A) 101028263(ATP8B2) 101029343(ATP8B1) 101029989 101035699(ATP10D) 101036311 101036736(ATP8B4) 101036857(ATP8B3) 101037071(ATP9A) 101038947(ATP11B) 101039829(ATP10B) 101042481(ATP11A) 101043679(ATP8A2) 101044798(ATP11C) 101045029 101047760(ATP8A1)
MMU: 
11980(Atp8a1) 11981(Atp9a) 11982(Atp10a) 231287(Atp10d) 241633(Atp8b4) 319767(Atp10b) 320571(Atp8b5) 320940(Atp11c) 50769(Atp8a2) 50770(Atp11a) 50771(Atp9b) 54667(Atp8b2) 54670(Atp8b1) 67331(Atp8b3) 76295(Atp11b)
RNO: 
289615(Atp8a1) 291411(Atp9b) 291555(Atp8b1) 299616(Atp8b3) 303056(Atp10b) 306600(Atp11a) 311396(Atp8b4) 317599(Atp11c) 360932(Atp10d) 361929(Atp11b) 365266(Atp10a) 685152 691125(Atp8b5p) 691889(Atp8a2) 84011(Atp9a)
CGE: 
100751265(Atp8b2) 100755398(Atp10d) 100756336(Atp11c) 100756975(Atp8a1) 100757984(Atp8b3) 100759968(Atp8b4) 100761170(Atp11a) 100763292(Atp8b1) 100763581(Atp8a2) 100765138(Atp9b) 100767948(Atp10b) 100773257(Atp11b) 100773673 100774392(Atp8b5) 100774607(Atp10a)
NGI: 
103724559(Atp10b) 103724688(Atp11c) 103727177(Atp8a2) 103729228(Atp8a1) 103733064(Atp8b4) 103734600(Atp10a) 103735761(Atp9a) 103735989(Atp11b) 103737399(Atp8b3) 103737870(Atp10d) 103746281(Atp11a) 103748127(Atp9b) 103751380(Atp8b2) 103751818(Atp8b1)
HGL: 
101699526(Atp9b) 101710735(Atp11a) 101712888(Atp8b4) 101715035(Atp8b1) 101716149(Atp10d) 101721324(Atp11c) 101721413(Atp9a) 101721856(Atp10a) 101721978(Atp8a2) 101722473(Atp10b) 101723336(Atp8b3) 101723838(Atp8b2) 101725306(Atp11b) 101725406(Atp8a1) 101726659
CCAN: 
OCU: 
100008757(ATP11B) 100339123(ATP9B) 100342068(ATP10A) 100342686(ATP11A) 100345551 100346151(ATP11C) 100347667(ATP8B2) 100349269(ATP8B4) 100353155(ATP10B) 100355104(ATP8A1) 100356348(ATP10D) 100358094 100358787(ATP8B1) 100358874 103345622(ATP9A) 108177012
TUP: 
102469376(ATP11A) 102475250(ATP8B4) 102475727 102481540(ATP9B) 102484095(ATP8B1) 102485526(ATP8B2) 102490800(ATP8B3) 102491504(ATP10D) 102492920 102493301(ATP9A) 102494353(ATP10B) 102494521(ATP8A1) 102495181(ATP10A) 102496769(ATP8A2) 102497224(ATP11B) 102498413 102501492
CFA: 
100687016(ATP8A2) 476190(ATP8B1) 476992(ATP11A) 477265(ATP9A) 478644(ATP11B) 481066(ATP11C) 482134(ATP10D) 483926(ATP9B) 486036 487549(ATP8B4) 488691(ATP10A) 489148(ATP10B) 490447(ATP8B2) 607976(ATP8A1) 611901 612245(ATP8B3)
AML: 
100464545(ATP9A) 100465107(ATP11B) 100465593(ATP8A1) 100465614(ATP10A) 100466989(ATP11C) 100468066(ATP10D) 100469171(ATP9B) 100471522(ATP8B2) 100473489 100475639 100477848(ATP8A2) 100481501(ATP8B1) 100483547(ATP11A) 100483624(ATP8B3) 100483656(ATP10B)
UMR: 
103657617(ATP11A) 103658426(ATP9B) 103664303 103664397 103664521(ATP10B) 103667074 103668397(ATP8B2) 103669831(ATP9A) 103672706(ATP10D) 103672786(ATP8A1) 103672848(ATP11C) 103676123(ATP8B1) 103676193(ATP11B) 103676730(ATP8B4) 103677110(ATP10A) 103681792(ATP8B3)
ORO: 
101365264(ATP8B4) 101365349(ATP11A) 101365955(ATP10A) 101368150(ATP10B) 101368232 101371545(ATP8B3) 101375340(ATP8A1) 101375661(ATP8B2) 101376128 101376321 101380277(ATP9A) 101382110(ATP10D) 101384560 101384631(ATP11C) 101385741(ATP9B) 101386905(ATP8B1) 101386995(ATP11B)
FCA: 
101080270(ATP9A) 101084112(ATP8B4) 101084853(ATP10B) 101085594(ATP8A2) 101085949(ATP8B2) 101086263 101091868(ATP8A1) 101093440(ATP10A) 101096779 101097392(ATP10D) 101097781(ATP11A) 101099184(ATP8B3) 101099649(ATP11B) 101099786(ATP11C) 101101003(ATP8B1) 101101004(ATP9B)
PTG: 
102950876(ATP11C) 102950974(ATP8A1) 102951690(ATP8B2) 102952637(ATP8B4) 102954785 102958788(ATP11B) 102958974 102959813(ATP8A2) 102961198(ATP8B1) 102961487(ATP10A) 102965063(ATP11A) 102965463(ATP10B) 102967933(ATP8B3) 102968918(ATP10D) 102969377(ATP9A) 102971797(ATP9B)
AJU: 
106967228(ATP8B4) 106967362(ATP11B) 106967608(ATP10B) 106967806(ATP10A) 106975042(ATP10D) 106977680(ATP9B) 106980385(ATP9A) 106981111(ATP8B1) 106981277 106982568(ATP11C) 106983703(ATP8B3) 106985516 106985937(ATP8A1) 106986704(ATP11A) 106987237(ATP8B2) 106988928
BTA: 
100137953(ATP8B4) 100336948(ATP10B) 107131233 317692(ATP8A1) 508723(ATP8A2) 510301(ATP9B) 510723(ATP10A) 512547(ATP11A) 516579(ATP9A) 516849 529689(ATP11C) 536495(ATP10D) 536660 541187(ATP8B1) 614392(ATP11B) 785713(ATP8B2)
BOM: 
102266551 102267112(ATP8B1) 102273088(ATP8A1) 102274109(ATP11A) 102275579(ATP8B3) 102277314(ATP9A) 102277904 102279750 102280627(ATP8A2) 102281261(ATP10B) 102283091(ATP11B) 102283926(ATP10A) 102284238(ATP11C) 102285765(ATP9B) 102286964(ATP8B2) 102287691(ATP8B4) 102288181(ATP10D)
BIU: 
109554149(ATP8B2) 109555346 109555446(ATP11C) 109557684(ATP11B) 109560023(ATP8A1) 109560028(ATP10D) 109561068(ATP8B3) 109562271(ATP10B) 109562506 109563001 109564378(ATP8B4) 109567019(ATP11A) 109567039 109567041 109567044 109567556(ATP9A) 109575112(ATP10A) 109577751(ATP9B) 109577909(ATP8B1)
PHD: 
102315710(ATP9B) 102316657(ATP8A1) 102317048(ATP10A) 102319539(ATP10B) 102323992(ATP8B4) 102324376(ATP8B3) 102326120(ATP11A) 102332635 102333539 102334126(ATP11B) 102336108 102336225(ATP10D) 102341726(ATP8B1) 102342622(ATP8B2) 102342862(ATP8A2) 102343566 102344655(ATP11C)
CHX: 
102169281(ATP8B3) 102169720(ATP8B1) 102173860(ATP11A) 102175139(ATP9A) 102175374(ATP11C) 102176951(ATP8A1) 102177243(ATP8B4) 102178344(ATP10D) 102178625 102180093(ATP8B2) 102184055(ATP10B) 102188453(ATP9B) 102190912(ATP11B) 102190971 102191462(ATP10A) 102191532(ATP8A2)
OAS: 
101103116(ATP8B2) 101107997(ATP10A) 101108356(ATP9B) 101108837(ATP8B4) 101109422 101110296(ATP11B) 101115135 101115500(ATP8B1) 101115632 101116987(ATP8B3) 101117246(ATP10B) 101117857(ATP11A) 101119308(ATP8A1) 101119494(ATP9A) 101122839(ATP11C) 101122863(ATP10D)
SSC: 
100136901(ATP9A) 100153006(ATP8B1) 100154720(ATP8B4) 100154901(ATP9B) 100156421 100158162(ATP10A) 100513137(ATP8B3) 100515393(ATP8A1) 100517341(ATP8B2) 100520087(ATP10D) 100523658(ATP11C) 100523747 100624673(ATP11B) 100625134 100626997(ATP10B) 110255868(ATP11A)
CFR: 
102505159(ATP10B) 102505599 102506116 102506353(ATP8A2) 102506670(ATP8B3) 102509688 102511701(ATP11C) 102512323 102513418(ATP8B1) 102514562(ATP11B) 102514997(ATP10D) 102516878(ATP9A) 102516996(ATP8A1) 102517778(ATP8B4) 102518000(ATP9B) 102518370(ATP10A) 102522523(ATP8B2) 102522954(ATP11A)
CDK: 
105085907(ATP11B) 105086034(ATP11C) 105089153(ATP8B2) 105089354(ATP8A1) 105090371(ATP8A2) 105090372 105090791(ATP10A) 105099946(ATP10D) 105102304 105102305 105103601(ATP8B1) 105103727(ATP10B) 105103851(ATP9B) 105104716(ATP8B4) 105105083(ATP9A) 105105123(ATP11A) 105106535(ATP8B3)
BACU: 
102997495(ATP11C) 102998822(ATP8A2) 103001978(ATP10B) 103004849(ATP8B1) 103005083(ATP8A1) 103007062(ATP11A) 103011230(ATP8B3) 103014101(ATP10D) 103014372(ATP10A) 103017885(ATP8B4) 103018033(ATP9A) 103019558(ATP11B) 103020035 103020087(ATP9B) 103020968(ATP8B2)
LVE: 
103071186(ATP8A1) 103071947(ATP10A) 103074178(ATP11A) 103075836 103077513(ATP11B) 103078380(ATP8B2) 103079662(ATP10D) 103080240(ATP10B) 103080744(ATP8B1) 103081382(ATP9B) 103081693(ATP8B3) 103083156(ATP9A) 103084501(ATP8A2) 103085794(ATP8B4) 103088887(ATP11C)
ECB: 
100052707(ATP9A) 100054112(ATP8B1) 100055432(ATP11C) 100059537(ATP8A2) 100061624(ATP10D) 100062211(ATP10A) 100062902(ATP8A1) 100065346(ATP9B) 100066562(ATP11B) 100066940(ATP11A) 100068071 100069998(ATP8B4) 100070951(ATP10B) 100146926(ATP8B3) 100629225(ATP8B2)
EPZ: 
EAI: 
106825550(ATP9A) 106827218 106830601(ATP11B) 106832151(ATP10B) 106832433 106832434(ATP8A2) 106833240(ATP10A) 106834218(ATP8B3) 106834921(ATP9B) 106835044(ATP8B1) 106838479(ATP8B4) 106839874(ATP11A) 106840106(ATP11C) 106841254(ATP10D) 106841270(ATP8A1) 106846236 106846989
MYB: 
102241136(ATP8B2) 102242688(ATP8A1) 102245482(ATP9B) 102246310(ATP8B4) 102246538(ATP9A) 102246618 102247769 102249584 102251041(ATP10A) 102251532(ATP10D) 102252418(ATP8B1) 102253439(ATP11B) 102257414(ATP10B) 102260200(ATP8B3) 102261343(ATP11C) 102263207(ATP8A2) 102263392(ATP11A)
MYD: 
102751732 102752128(ATP8A2) 102752686(ATP11B) 102752849(ATP8B1) 102753557(ATP8B2) 102756873 102756877(ATP11C) 102757359(ATP10A) 102758716(ATP8B4) 102760838(ATP8B3) 102763495(ATP9B) 102768469(ATP11A) 102770925(ATP8A1) 102771707(ATP10D) 102773187(ATP9A) 102773506 102773828(ATP10B)
HAI: 
109373496(ATP8B2) 109374158(ATP8A1) 109381719(ATP8B1) 109381838(ATP9A) 109383187(ATP9B) 109383943(ATP11A) 109387513(ATP8A2) 109388679(ATP11C) 109390562(ATP8B3) 109393741 109394177(ATP8B4) 109394221(ATP10B) 109395051(ATP10D) 109396146(ATP10A) 109396385(ATP11B)
RSS: 
PALE: 
102878271(ATP8B2) 102879357(ATP8B4) 102881604(ATP11C) 102882432(ATP8A1) 102884412(ATP8B1) 102884486(ATP11A) 102886133(ATP10B) 102886526(ATP9A) 102888141(ATP11B) 102888143(ATP10A) 102888432 102888531(ATP10D) 102892388(ATP8B3) 102892598(ATP9B) 102894916(ATP8A2)
LAV: 
100655178(ATP11A) 100655706(ATP8B1) 100657194(ATP11C) 100658776(ATP11B) 100663835(ATP10A) 100665039(ATP8A1) 100665525 100665810(ATP8A2) 100666617(ATP9B) 100667043(ATP10D) 100668804 100672945(ATP9A) 100673130(ATP8B4) 100676439(ATP8B2) 100677128(ATP10B) 104847397
TMU: 
MDO: 
100012603(ATP11C) 100016294(ATP8B1) 100018023(ATP8B3) 100019520(ATP10D) 100020493(ATP8B2) 100020627(ATP8A1) 100022587(ATP11A) 100022728(ATP9A) 100023022(ATP9B) 100024643(ATP8A2) 100028308 100030456(ATP10B) 100616715(ATP11B) 100617055(ATP10A) 100618061(ATP8B4)
SHR: 
100915222(ATP8B3) 100917108(ATP8A1) 100917134 100917244(ATP10A) 100918632(ATP11B) 100918706 100919988(ATP9A) 100921779(ATP11A) 100921902(ATP11C) 100922437(ATP8B1) 100924402(ATP8B2) 100926891(ATP9B) 100927590 100927739 100927847(ATP8A2) 100932995(ATP8B4) 100934378(ATP10D) 100935347(ATP10B) 105749248
OAA: 
100073697(ATP11B) 100073923(ATP10A) 100074214(ATP10B) 100075863(ATP8B3) 100077977(ATP9A) 100078463(ATP9B) 100078594(ATP11C) 100079760(ATP8B1) 100081427(ATP10D) 100084825(ATP11A) 100087139 100089451(ATP8A1) 100090122(ATP8A2)
GGA: 
416159(ATP10B) 418685(ATP10A) 418749(ATP11A) 418936(ATP8A2) 419345(ATP9A) 420817(ATP9B) 422254(ATP11C) 422768(ATP10D) 422776(ATP8A1) 424964(ATP11B) 426857(ATP8B1) 428328(ATP8B3) 431656(ATP8B4) 770035(ATP8B2)
MGP: 
100538381(ATP11C) 100539283(ATP10A) 100541990(ATP9A) 100542612 100543170(ATP10B) 100545574(ATP10D) 100545930(ATP9B) 100546259(ATP11B) 100546894(ATP8A2) 100547261(ATP8A1) 100547912(ATP8B3) 100550069(ATP11A) 100550826 104914730(ATP8B1)
CJO: 
107305707(ATP8B1) 107305798 107306242(ATP11A) 107307517(ATP10A) 107308305(ATP8A2) 107309753(ATP9B) 107312720(ATP11C) 107313762(ATP10D) 107313794(ATP8A1) 107318131(ATP11B) 107320454(ATP10B) 107323200(ATP9A) 107324472(ATP8B2) 107325663(ATP8B3)
APLA: 
101789906(ATP10B) 101790964(ATP9A) 101791602(ATP11A) 101791790(ATP8B3) 101793669(ATP11B) 101794313(ATP9B) 101795223(ATP10A) 101796204(ATP8B1) 101796582(ATP8B2) 101799242(ATP11C) 101799384(ATP8A2) 101800696 101801741(ATP10D) 101802029(ATP8A1) 101803847
ACYG: 
106030765(ATP10D) 106032042(ATP11B) 106034355(ATP10B) 106035718(ATP10A) 106037416(ATP11C) 106038342(ATP9B) 106040353 106041621(ATP9A) 106044906(ATP8B1) 106045626(ATP8B3) 106046436(ATP11A) 106048052(ATP8A1) 106048513(ATP8B2) 106048544 106049613
TGU: 
100219227(ATP11B) 100219240(ATP8B2) 100220565(ATP8A2) 100220790(ATP8B1) 100220889(ATP11A) 100221408 100223014(ATP11C) 100223812(ATP10A) 100224155(ATP9B) 100227780(ATP10B) 100228586(ATP8A1) 100228886(ATP10D) 100229226(ATP9A)
GFR: 
102031499(ATP9B) 102033825(ATP11B) 102034304 102036290(ATP10B) 102037905(ATP8B3) 102038135(ATP8B2) 102038405(ATP11C) 102038476(ATP8A1) 102039334(ATP10D) 102040043(ATP10A) 102040876(ATP8A2) 102044892(ATP11A) 102045073(ATP9A)
FAB: 
101806184(ATP10B) 101810545(ATP11C) 101810751(ATP11B) 101810902(ATP8B3) 101811109(ATP8A2) 101811423(ATP8B1) 101812034(ATP8A1) 101812745(ATP9B) 101814904(ATP9A) 101815983(ATP10D) 101816724(ATP10A) 101818211(ATP11A) 101819533 101821153(ATP8B2) 101822280
PHI: 
102101068(ATP10A) 102101248(ATP8B2) 102102103(ATP8B3) 102103842(ATP8A1) 102105284(ATP8A2) 102105351(ATP10D) 102108883(ATP9A) 102109610(ATP11C) 102109779(ATP10B) 102111315(ATP11A) 102111642(ATP11B) 102112947 102113319(ATP9B) 102113467(ATP8B1)
PMAJ: 
107198652(ATP8B1) 107199390 107199991(ATP9B) 107203029(ATP8A1) 107203476(ATP10D) 107203922(ATP11C) 107208690(ATP11B) 107208919(ATP11A) 107209102(ATP10A) 107210219(ATP8A2) 107210902(ATP10B) 107213376(ATP9A) 107214582(ATP8B2) 107215363(ATP8B3) 107216205
CCW: 
104686037(ATP10A) 104686322(ATP11A) 104686567 104687790(ATP9A) 104688001(ATP11B) 104688857(ATP9B) 104689880(ATP8A2) 104690647(ATP10D) 104690658(ATP8A1) 104691364(ATP11C) 104693547(ATP10B) 104696949(ATP8B3) 104698613(ATP8B1) 104698663(ATP8B2)
FPG: 
101910802 101910973(ATP10B) 101911821(ATP8B3) 101913038(ATP9B) 101913068(ATP8A2) 101916078(ATP11B) 101917032(ATP11C) 101919027(ATP9A) 101919278(ATP10A) 101922803(ATP11A) 101923166(ATP10D) 101923260(ATP8B1) 101923527 101924039(ATP8A1) 101924949(ATP8B2)
FCH: 
102045913(ATP8B1) 102046707(ATP11A) 102047378(ATP9A) 102047521(ATP10A) 102048251(ATP11B) 102049838(ATP8A1) 102050149(ATP8B2) 102050221 102050543(ATP10B) 102053221(ATP9B) 102053969(ATP8B3) 102054952(ATP11C) 102056359(ATP10D) 102056518(ATP8A2)
CLV: 
102083976(ATP8B3) 102086533(ATP11B) 102087502(ATP9A) 102090638(ATP10D) 102091646(ATP9B) 102094319(ATP8B2) 102094964(ATP11A) 102096288 102096479(ATP8A2) 102096539(ATP8B1) 102097439(ATP11C) 102097598 102097812(ATP10A) 102098463(ATP8A1) 102098829(ATP10B)
EGZ: 
104123295(ATP11B) 104125012(ATP8B1) 104125231(ATP10A) 104125474(ATP9B) 104125973 104127750(ATP8B3) 104128461(ATP8A1) 104129376(ATP10D) 104129909(ATP11C) 104131691(ATP8A2) 104132149(ATP9A) 104132463(ATP11A) 104133647(ATP10B) 104133886
AAM: 
106482232(ATP11B) 106482994(ATP9B) 106483705 106484778(ATP11C) 106487207(ATP8B1) 106490163(ATP10D) 106490188(ATP8A1) 106490655(ATP11A) 106491384 106491756(ATP9A) 106492908 106493562(ATP10B) 106494019(ATP10A) 106499352(ATP8B3) 106500401(ATP8A2)
ASN: 
102367742(ATP10A) 102368073(ATP9B) 102370899(ATP10B) 102373411(ATP8B4) 102373780(ATP11B) 102375504(ATP11A) 102376473(ATP8A1) 102377086(ATP8B1) 102377908(ATP8B2) 102379283(ATP8B3) 102380315(ATP10D) 102381830(ATP11C) 102382122(ATP9A) 102384527 102386600 102386728 102386812(ATP8A2) 102388665
AMJ: 
102559524(ATP9A) 102562158(ATP11B) 102565160(ATP8A2) 102565165(ATP10D) 102565789(ATP8B1) 102567957(ATP8B3) 102568510(ATP8B4) 102571061(ATP8A1) 102571860 102574680(ATP10B) 102575900(ATP8B2) 102576583(ATP11A) 106736697(ATP10A) 106736802(ATP9B) 106737006(ATP11C) 109285892
PSS: 
102443448(ATP8A1) 102443594(ATP8B3) 102444118(ATP11A) 102446401(ATP10D) 102448780(ATP10B) 102451838(ATP9B) 102452052(ATP8A2) 102453318(ATP10A) 102461705(ATP8B1) 102462311(ATP8B4) 102462785(ATP8B2) 102462934(ATP9A) 102463452(ATP11B) 102463788(ATP11C)
CMY: 
102929736(ATP11B) 102930207(ATP9B) 102931155(ATP8A2) 102933506(ATP11A) 102934142(ATP8B1) 102935449(ATP10B) 102937383(ATP10D) 102938841(ATP11C) 102942998(ATP8B3) 102946813(ATP8A1) 102946868(ATP10A) 102947737 102947776(ATP8B4) 102948228(ATP8B2) 102948348(ATP9A)
CPIC: 
101930978(ATP8A2) 101933641(ATP9B) 101933833(ATP9A) 101933928(ATP11A) 101934056(ATP11C) 101934989(ATP8B1) 101936517 101937136(ATP10D) 101938132(ATP8B2) 101942699(ATP11B) 101943113(ATP10B) 101944947(ATP8B4) 101945397(ATP8A1) 101946059(ATP10A) 101952534(ATP8B3)
ACS: 
100552359 100553567(atp10a) 100554182(atp8a2) 100556007(atp9a) 100556669(atp8b2) 100556728(atp10d) 100557766(atp8b1) 100558859(atp11a) 100559061(atp9b) 100559939(atp10b) 100562936(atp11b) 100564127(atp8a1) 100566455(atp11c) 103282215 103282872 103282975
PVT: 
110071810(ATP9A) 110072650(ATP8B3) 110072901(ATP9B) 110075221(ATP8A1) 110076458(ATP8A2) 110078421(ATP10D) 110079340(ATP11A) 110082805 110084959(ATP11C) 110086064(ATP11B) 110087523(ATP10B) 110087725(ATP10A) 110088487(ATP8B2) 110091409(ATP8B1)
PBI: 
GJA: 
107105541 107106632 107109858(ATP8B3) 107110921(ATP11A) 107110930(ATP8B4) 107111202(ATP8B1) 107111516(ATP9B) 107111745(ATP10D) 107112573(ATP8A1) 107112633(ATP8A2) 107114379(ATP10B) 107116109(ATP11C) 107117106(ATP8B2) 107117518(ATP10A) 107119461(ATP11B) 107120478(ATP9A)
XLA: 
XTR: 
100135380(atp11b) 100145017(atp8b4) 100485769(atp11a) 100489696(atp10b) 100490503(atp8b2) 100490666(atp8b3) 100494528(atp10a) 100497381(atp9b) 100498300(atp11c) 101730757(atp8a2) 394841(atp9a) 549378(atp10d) 594952(atp8b1) 733571(atp8a1)
NPR: 
108784255(ATP9B) 108791701(ATP11A) 108792398 108792587(ATP10A) 108792853(ATP8B3) 108793200(ATP11C) 108793825(ATP8A1) 108793992(ATP10D) 108794647 108795175(ATP8A2) 108795669(ATP9A) 108795768(ATP11B) 108796986 108799507(ATP10B) 108801231 108804471 108804485
DRE: 
100148342(atp8b1) 100329583(si:dkey-211e20.10) 100330943(atp8a2) 100330945(atp8b5a) 101886226(atp9a) 323754(atp8b2) 368385(atp11c) 559291(atp8b4) 562925(atp11a) 563932(atp10b) 567172(atp10a) 568160(atp9b) 571658(atp10d)
SRX: 
SANH: 
SGH: 
CCAR: 
IPU: 
108255417 108256710(atp8a2) 108257241(atp9b) 108258841(atp11a) 108263430(atp10d) 108265990(atp8b2) 108268869(atp11c) 108269037(atp8a1) 108270623(atp11b) 108270635 108270636 108272065(atp10a) 108275428(atp10b) 108275434(atp8b4) 108276072(atp9a) 108277118 108278845(atp8b1)
AMEX: 
103023484(atp10a) 103023721 103024439(atp8a2) 103025813(atp11c) 103025894(atp8b4) 103026348(atp8a1) 103029014(atp10d) 103029216(atp8b2) 103032592(atp8b1) 103032624(atp9a) 103037606(atp9b) 103043353(atp11b) 103044851(atp10b) 103046490 103046796 111188760 111188793
TRU: 
101062591(atp8b1) 101062719 101063241 101063382(atp10a) 101064206 101065186 101065715(atp10d) 101066624(atp11b) 101067743(atp11a) 101068743(atp9a) 101068847(atp10b) 101069381(atp11c) 101069525(atp8a2) 101069669(atp8b2) 101074349(atp8b4) 101075533(atp8a1) 101075811 105418407
TNG: 
LCO: 
104921060 104922573(atp10d) 104923487(atp11c) 104923499(atp11b) 104923879(atp9a) 104924965(atp8a2) 104927703 104927925(atp8a1) 104929111(atp11a) 104929430 104931078(atp9b) 104932684 104934468 104936661(atp10a) 104938349(atp8b1) 104938836(atp10b) 104940669(atp8b4) 109137803
NCC: 
MZE: 
OLA: 
XMA: 
PRET: 
103456637(atp8a2) 103459068(atp10d) 103460336(atp9b) 103460765(atp8b1) 103463112(atp11b) 103463644 103463921(atp10a) 103466435(atp8b4) 103467853(atp9a) 103470713 103471196(atp10b) 103471508(atp8a1) 103471617(atp11c) 103474011 103474022 103475257(atp11a) 103478149 103479768
CSEM: 
LCF: 
HCQ: 
BPEC: 
SASA: 
ELS: 
SFM: 
LCM: 
102346182(ATP11C) 102347589(ATP11B) 102350213 102350555(ATP9B) 102351430(ATP11A) 102352111 102352802(ATP8A1) 102353398(ATP9A) 102353470(ATP8B4) 102354183 102354915(ATP8A2) 102355245(ATP10D) 102361071(ATP8B3) 102361964(ATP10A) 102362406(ATP8B2) 102365234 102366329(ATP8B1) 102366622(ATP10B)
CMK: 
103175876(atp8a1) 103177125(atp10a) 103177543(atp11a) 103177855 103178138(atp10d) 103178237(atp11c) 103183226(atp9b) 103183262(atp8a2) 103183758(atp10b) 103184865(atp8b1) 103186938(atp8b4) 103187987(atp11b) 103191032(atp9a)
BFO: 
CIN: 
SPU: 
APLC: 
SKO: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
Dsimw501_GD20604(Dsim_GD20604) Dsimw501_GD23608(Dsim_GD23608) Dsimw501_GD23885(Dsim_GD23885) Dsimw501_GD24493(Dsim_GD24493) Dsimw501_GD24836(Dsim_GD24836) Dsimw501_GD25762(Dsim_GD25762)
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
MDE: 
AGA: 
CQU: 
AME: 
BIM: 
BTER: 
SOC: 
AEC: 
ACEP: 
PBAR: 
HST: 
CFO: 
LHU: 
PGC: 
NVI: 
TCA: 
655986(Atp9b) 656757 658562(ATP8B2) 663307
DPA: 
NVL: 
BMOR: 
DPL: 
PMAC: 
PXY: 
API: 
DNX: 
PHU: 
ZNE: 
FCD: 
DPX: 
ISC: 
TUT: 
CEL: 
CBR: 
CBG11664(Cbr-tat-2) CBG11754(Cbr-tat-1) CBG16933(Cbr-tat-5) CBG18322(Cbr-tat-3)
NAI: 
BMY: 
LOA: 
TSP: 
HRO: 
LGI: 
CRG: 
MYI: 
OBI: 
LAK: 
SMM: 
SHX: 
OVI: 
NVE: 
EPA: 
ADF: 
HMG: 
TAD: 
AQU: 
ATH: 
ALY: 
CRB: 
CSAT: 
EUS: 
BRP: 
BNA: 
BOE: 
THJ: 
CPAP: 
CIT: 
CIC: 
TCC: 
GRA: 
GHI: 
EGR: 
GMX: 
PVU: 
VRA: 
VAR: 
CCAJ: 
MTR: 
CAM: 
ADU: 
AIP: 
LJA: 
Lj0g3v0004229.1(Lj0g3v0004229.1) Lj0g3v0104529.1(Lj0g3v0104529.1) Lj0g3v0116069.1(Lj0g3v0116069.1) Lj0g3v0116069.2(Lj0g3v0116069.2) Lj0g3v0164329.1(Lj0g3v0164329.1) Lj0g3v0164329.2(Lj0g3v0164329.2) Lj0g3v0164329.3(Lj0g3v0164329.3) Lj0g3v0164329.4(Lj0g3v0164329.4) Lj0g3v0164329.5(Lj0g3v0164329.5) Lj0g3v0253989.1(Lj0g3v0253989.1) Lj0g3v0253989.2(Lj0g3v0253989.2) Lj0g3v0289499.1(Lj0g3v0289499.1) Lj0g3v0289499.2(Lj0g3v0289499.2) Lj0g3v0289499.3(Lj0g3v0289499.3) Lj0g3v0312389.1(Lj0g3v0312389.1) Lj0g3v0312389.2(Lj0g3v0312389.2) Lj1g3v2471250.1(Lj1g3v2471250.1) Lj1g3v2471250.2(Lj1g3v2471250.2) Lj2g3v1002560.1(Lj2g3v1002560.1) Lj2g3v1002560.2(Lj2g3v1002560.2) Lj2g3v1192980.1(Lj2g3v1192980.1) Lj2g3v1353620.1(Lj2g3v1353620.1) Lj2g3v1353620.2(Lj2g3v1353620.2) Lj3g3v0323390.1(Lj3g3v0323390.1) Lj3g3v0323390.2(Lj3g3v0323390.2) Lj3g3v2664380.1(Lj3g3v2664380.1) Lj3g3v2664380.2(Lj3g3v2664380.2) Lj3g3v2664390.1(Lj3g3v2664390.1) Lj3g3v2810120.1(Lj3g3v2810120.1) Lj3g3v2810120.2(Lj3g3v2810120.2) Lj4g3v1772600.1(Lj4g3v1772600.1)
LANG: 
FVE: 
PPER: 
PMUM: 
MDM: 
PXB: 
ZJU: 
CSV: 
CMO: 
MCHA: 
RCU: 
JCU: 
HBR: 
POP: 
POPTR_0001s11630g(POPTRDRAFT_751108) POPTR_0001s204401 POPTR_0001s34920g(POPTRDRAFT_797847) POPTR_0003s04180g(POPTRDRAFT_553529) POPTR_0003s14900g(POPTRDRAFT_757716) POPTR_0006s10970g(POPTRDRAFT_560995) POPTR_0008s01500g(POPTRDRAFT_820189) POPTR_0008s01520g(POPTRDRAFT_765109) POPTR_0008s11060g(POPTRDRAFT_720837) POPTR_0008s19560g(POPTRDRAFT_803861) POPTR_0010s04910g(POPTRDRAFT_230718) POPTR_0010s14270g(POPTRDRAFT_566702) POPTR_0010s25240g(POPTRDRAFT_770737) POPTR_0010s25250g(POPTRDRAFT_725358) POPTR_0012s05450g(POPTRDRAFT_421641) POPTR_0016s14500g(POPTRDRAFT_254443) POPTR_0017s04520g
VVI: 
SLY: 
SPEN: 
SOT: 
CANN: 
NTA: 
NSY: 
NTO: 
INI: 
SIND: 
HAN: 
BVG: 
SOE: 
NNU: 
OSA: 
DOSA: 
Os01t0277600-00(Os01g0277600) Os03t0326000-01(Os03g0326000) Os03t0326100-01(Os03g0326100) Os03t0334700-01(Os03g0334700) Os05t0100600-01(Os05g0100600) Os06t0488600-01(Os06g0488600) Os06t0565900-01(Os06g0565900) Os08t0379200-01(Os08g0379200) Os10t0412000-01(Os10g0412000) Os10t0412050-00(Os10g0412050) Os11t0446500-00(Os11g0446500)
OBR: 
BDI: 
SBI: 
ZMA: 
SITA: 
PDA: 
EGU: 
MUS: 
DCT: 
ATR: 
SMO: 
PPP: 
CRE: 
VCN: 
MNG: 
OLU: 
OTA: 
BPG: 
MIS: 
CSL: 
CVR: 
APRO: 
CME: 
GSL: 
CCP: 
SCE: 
YAL026C(DRS2) YDR093W(DNF2) YER166W(DNF1) YIL048W(NEO1) YMR162C(DNF3)
AGO: 
ERC: 
KLA: 
LTH: 
VPO: 
ZRO: 
CGR: 
NCS: 
NCAS_0A03670(NCAS0A03670) NCAS_0A13450(NCAS0A13450) NCAS_0B04000(NCAS0B04000) NCAS_0D00950(NCAS0D00950) NCAS_0F01710(NCAS0F01710)
NDI: 
NDAI_0A02590(NDAI0A02590) NDAI_0C06110(NDAI0C06110) NDAI_0H02560(NDAI0H02560) NDAI_0H03190(NDAI0H03190) NDAI_0J01530(NDAI0J01530)
TPF: 
TPHA_0B03400(TPHA0B03400) TPHA_0C01120(TPHA0C01120) TPHA_0C04600(TPHA0C04600) TPHA_0H02720(TPHA0H02720) TPHA_0K00950(TPHA0K00950)
TBL: 
TBLA_0A04620(TBLA0A04620) TBLA_0B09370(TBLA0B09370) TBLA_0D04110(TBLA0D04110) TBLA_0E04190(TBLA0E04190) TBLA_0F03810(TBLA0F03810) TBLA_0J01460(TBLA0J01460)
TDL: 
TDEL_0A01330(TDEL0A01330) TDEL_0G02790(TDEL0G02790) TDEL_0H02100(TDEL0H02100) TDEL_0H03790(TDEL0H03790)
KAF: 
KAFR_0A02410(KAFR0A02410) KAFR_0B02510(KAFR0B02510) KAFR_0B04880(KAFR0B04880) KAFR_0I01860(KAFR0I01860) KAFR_0K00630(KAFR0K00630)
PPA: 
DHA: 
PIC: 
PGU: 
SPAA: 
LEL: 
CAL: 
CAALFM_C104630CA(CaO19.783) CAALFM_C303250WA(CaO19.323) CAALFM_C307230WA(CaO19.6778) CAALFM_C403110WA(CaO19.2680) CAALFM_C500570WA(CaO19.932)
CTP: 
COT: 
CDU: 
CTEN: 
YLI: 
CLU: 
CLUS: 
CAUR: 
NCR: 
NTE: 
NEUTE1DRAFT149255(NEUTE1DRAFT_149255) NEUTE1DRAFT58154(NEUTE1DRAFT_58154) NEUTE1DRAFT58590(NEUTE1DRAFT_58590) NEUTE1DRAFT79192(NEUTE1DRAFT_79192) NEUTE1DRAFT82209(NEUTE1DRAFT_82209)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
FVR: 
FOX: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
PLJ: 
VAL: 
VDA: 
CFJ: 
ELA: 
PFY: 
SSL: 
BFU: 
MBE: 
PSCO: 
GLZ: 
ANI: 
AFM: 
AOR: 
AOR_1_1364054(AO090011000813) AOR_1_152094(AO090120000088) AOR_1_2132154(AO090003001200) AOR_1_278114(AO090701000148)
ANG: 
ANI_1_1060104(An12g08790) ANI_1_2000184(An04g06840) ANI_1_258134(An15g01510) ANI_1_558104(An12g04500)
AFV: 
ACT: 
NFI: 
PCS: 
PDP: 
CIM: 
CPW: 
PBL: 
PAAG_04592 PAAG_06151 PAAG_12472(PAAG_07970) PAAG_12519(PAAG_08231)
PBN: 
URE: 
ABE: 
TVE: 
AJE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
SPO: 
CNE: 
CNB: 
CGI: 
TMS: 
PPL: 
TVS: 
DSQ: 
PCO: 
SHS: 
HIR: 
PSQ: 
ADL: 
FME: 
GTR: 
LBC: 
MPR: 
MRR: 
CCI: 
SCM: 
ABP: 
AGABI1DRAFT117898(AGABI1DRAFT_117898) AGABI1DRAFT119321(AGABI1DRAFT_119321) AGABI1DRAFT121881(AGABI1DRAFT_121881) AGABI1DRAFT122765(AGABI1DRAFT_122765) AGABI1DRAFT67998(AGABI1DRAFT_67998)
ABV: 
AGABI2DRAFT122163(AGABI2DRAFT_122163) AGABI2DRAFT153664(AGABI2DRAFT_153664) AGABI2DRAFT185198(AGABI2DRAFT_185198) AGABI2DRAFT198829(AGABI2DRAFT_198829) AGABI2DRAFT198857(AGABI2DRAFT_198857)
CPUT: 
SLA: 
WSE: 
WIC: 
UMA: 
PFP: 
MGL: 
PGR: 
MLR: 
ECU: 
EIN: 
EHE: 
ERO: 
NCE: 
MBR: 
SRE: 
DDI: 
DPP: 
DFA: 
EHI: 
EHI_049640(21.t00048) EHI_096620(6.t00057) EHI_140130(8.t00012) EHI_141350(309.t00009) EHI_168260(191.t00016)
EDI: 
EIV: 
ACAN: 
PFA: 
PFD: 
PFH: 
PYO: 
PCB: 
PCHAS_143680(PC000483.03.0) PCHAS_144030(PC001079.02.0)
PBE: 
PKN: 
PVX: 
PCY: 
TAN: 
TPV: 
TOT: 
BEQ: 
BBO: 
BBOV_III007600(17.m07665) BBOV_IV001830(21.m02975) BBOV_IV003630(21.m02979)
CPV: 
CHO: 
TGO: 
TET: 
PTM: 
SMIN: 
v1.2.003745.t1(symbB.v1.2.003745.t1) v1.2.008818.t1(symbB.v1.2.008818.t1) v1.2.008820.t1(symbB.v1.2.008820.t1) v1.2.009532.t1(symbB.v1.2.009532.t1) v1.2.009535.t1(symbB.v1.2.009535.t1) v1.2.011936.t1(symbB.v1.2.011936.t1) v1.2.014487.t1(symbB.v1.2.014487.t1) v1.2.017624.t1(symbB.v1.2.017624.t1) v1.2.017624.t2(symbB.v1.2.017624.t2) v1.2.020008.t1(symbB.v1.2.020008.t1) v1.2.025610.t1(symbB.v1.2.025610.t1) v1.2.025613.t1(symbB.v1.2.025613.t1) v1.2.039169.t1(symbB.v1.2.039169.t1)
PTI: 
PHATRDRAFT_52368(ATPase-P4)
FCY: 
TPS: 
AAF: 
PIF: 
PSOJ: 
SPAR: 
EHX: 
GTT: 
TBR: 
Tb11.02.0850 Tb927.4.1510(Tb04.2L9.780) Tb927.6.3550(Tb06.2N9.170)
TCR: 
LMA: 
LIF: 
LDO: 
LMI: 
LBZ: 
NGR: 
TVA: 
GLA: 
 » show all
Taxonomy
Reference
1  [PMID:8136700]
  Authors
Morris MB, Auland ME, Xu YH, Roufogalis BD.
  Title
Characterization of the Mg(2+)-ATPase activity of the human erythrocyte membrane.
  Journal
Biochem. Mol. Biol. Int. 31 (1993) 823-32.
Reference
2  [PMID:8839453]
  Authors
Vermeulen WP, Briede JJ, Roelofsen B.
  Title
Manipulation of the phosphatidylethanolamine pool in the human red cell membrane affects its Mg2+-ATPase activity.
  Journal
Mol. Membr. Biol. 13 (1996) 95-102.
Reference
3  [PMID:9099684]
  Authors
Suzuki H, Kamakura M, Morii M, Takeguchi N.
  Title
The phospholipid flippase activity of gastric vesicles.
  Journal
J. Biol. Chem. 272 (1997) 10429-34.
Reference
4  [PMID:7971987]
  Authors
Auland ME, Roufogalis BD, Devaux PF, Zachowski A.
  Title
Reconstitution of ATP-dependent aminophospholipid translocation in proteoliposomes.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 91 (1994) 10938-42.
Reference
5  [PMID:16452632]
  Authors
Alder-Baerens N, Lisman Q, Luong L, Pomorski T, Holthuis JC
  Title
Loss of P4 ATPases Drs2p and Dnf3p disrupts aminophospholipid transport and asymmetry in yeast post-Golgi secretory vesicles.
  Journal
Mol. Biol. Cell. 17 (2006) 1632-42.
Reference
6  [PMID:20053675]
  Authors
Lopez-Marques RL, Poulsen LR, Hanisch S, Meffert K, Buch-Pedersen MJ, Jakobsen MK, Pomorski TG, Palmgren MG
  Title
Intracellular targeting signals and lipid specificity determinants of the ALA/ALIS P4-ATPase complex reside in the catalytic ALA alpha-subunit.
  Journal
Mol. Biol. Cell. 21 (2010) 791-801.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system