KEGG   ENZYME: 3.6.3.22Help
Entry
EC 3.6.3.22                 Enzyme                                 

Name
nonpolar-amino-acid-transporting ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances
BRITE hierarchy
Sysname
ATP phosphohydrolase (nonpolar-amino-acid-transporting)
Reaction(IUBMB)
ATP + H2O + nonpolar amino acidout = ADP + phosphate + nonpolar amino acidin [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
nonpolar amino acid
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
nonpolar amino acid
Comment
ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. Comprises bacterial enzymes that import Leu, Ile and Val.
History
EC 3.6.3.22 created 2000
Orthology
K10822  
nonpolar-amino-acid-transporting ATPase
Genes
REH: 
H16_A1244(h16_A1244) H16_A1245(h16_A1245) H16_A1542(h16_A1542)
Taxonomy
Reference
1  [PMID:7569321]
  Authors
Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH Jr.
  Title
Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases.
  Journal
Res. Microbiol. 146 (1995) 271-8.
Reference
2  [PMID:9889977]
  Authors
Saier MH Jr.
  Title
Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya.
  Journal
Adv. Microb. Physiol. 40 (1998) 81-136.
Reference
3
  Authors
Griffiths, J.K. and Sansom, C.E.
  Title
The Transporter Factsbook, Academic Press, San Diego, 1998.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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