| Entry |
|
|---|
| Name |
cadmium-transporting ATPase |
|---|
| Class |
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of
substances
 |
|---|
| Sysname |
ATP phosphohydrolase (heavy-metal-exporting) |
|---|
| Reaction(IUBMB) |
ATP + H2O = ADP + phosphate [RN:R00086] |
|---|
| Reaction(KEGG) |
R00086
 |
|---|
| Substrate |
ATP [CPD:C00002];
H2O [CPD:C00001] |
|---|
| Product |
ADP [CPD:C00008];
phosphate [CPD:C00009] |
|---|
| Comment |
ABC-type (ATP-binding cassette-type) ATPase, characterised by the
presence of two similar ATP-binding domains. Does not undergo
phosphorylation during the transport process. A yeast enzyme that
exports some heavy metals, especially Cd2+, from the cytosol into
the vacuole. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:8626454]
Li ZS, Szczypka M, Lu YP, Thiele DJ, Rea PA.
The yeast cadmium factor protein (YCF1) is a vacuolar glutathione
S-conjugate pump.
J. Biol. Chem. 271 (1996) 6509-17.
Saccharomyces cerevisiae [GN:sce] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:9889977]
Saier MH Jr.
Molecular phylogeny as a basis for the classification of transport
proteins from bacteria, archaea and eukarya.
Adv. Microb. Physiol. 40 (1998) 81-136.
bacteria |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.6.3.46
IUBMB Enzyme Nomenclature: 3.6.3.46
ExPASy - ENZYME nomenclature database: 3.6.3.46
BRENDA, the Enzyme Database: 3.6.3.46 |
|---|
