KEGG   ENZYME: 3.6.3.48Help
Entry
EC 3.6.3.48                 Enzyme                                 

Name
alpha-factor-transporting ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances
BRITE hierarchy
Sysname
ATP phosphohydrolase (alpha-factor-transporting)
Reaction(IUBMB)
ATP + H2O + alpha-factorin = ADP + phosphate + alpha-factorout [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
alpha-factor
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
alpha-factor
Comment
ABC-type (ATP-binding cassette-type) ATPase, characterized by the presence of two similar ATP-binding domains. Does not undergo phosphorylation during the transport process. A yeast enzyme that exports the alpha-factor sex pheromone.
History
EC 3.6.3.48 created 2000
Reference
1  [PMID:8095825]
  Authors
Michaelis S.
  Title
STE6, the yeast a-factor transporter.
  Journal
Semin. Cell. Biol. 4 (1993) 17-27.
  Organism
Saccharomyces cerevisiae
Reference
2  [PMID:9889977]
  Authors
Saier MH Jr.
  Title
Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya.
  Journal
Adv. Microb. Physiol. 40 (1998) 81-136.
  Organism
bacteria
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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