KEGG   ENZYME: 3.6.3.53Help
Entry
EC 3.6.3.53                 Enzyme                                 

Name
Ag+-exporting ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to catalyse transmembrane movement of substances
BRITE hierarchy
Sysname
ATP phosphohydrolase (Ag+-exporting)
Reaction(IUBMB)
ATP + H2O + Ag+in = ADP + phosphate + Ag+out [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
Ag+ [CPD:C06710]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
Ag+ [CPD:C06710]
Comment
A P-type ATPase that exports Ag+ ions from pathogenic microorganisms as well as from some animal tissues.
History
EC 3.6.3.53 created 2000
Reference
1  [PMID:9930866]
  Authors
Gupta A, Matsui K, Lo JF, Silver S.
  Title
Molecular basis for resistance to silver cations in Salmonella.
  Journal
Nat. Med. 5 (1999) 183-8.
Reference
2  [PMID:10448119]
  Authors
Bury NR, Grosell M, Grover AK, Wood CM.
  Title
ATP-dependent silver transport across the basolateral membrane of rainbow trout gills.
  Journal
Toxicol. Appl. Pharmacol. 159 (1999) 1-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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