KEGG   ENZYME: 3.6.4.11Help
Entry
EC 3.6.4.11                 Enzyme                                 

Name
nucleoplasmin ATPase
Class
Hydrolases;
Acting on acid anhydrides;
Acting on acid anhydrides to facilitate cellular and subcellular movement
BRITE hierarchy
Sysname
ATP phosphohydrolase (nucleosome-assembling)
Reaction(IUBMB)
ATP + H2O = ADP + phosphate [RN:R00086]
Reaction(KEGG)
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009]
Comment
An acidic nuclear protein that is active in the ATP-dependent assembly of nucleosome cores, in decondensation of sperm chromatin and in other histone-involving processes.
History
EC 3.6.4.11 created 2000
Reference
1  [PMID:8098530]
  Authors
Laskey RA, Mills AD, Philpott A, Leno GH, Dilworth SM, Dingwall C.
  Title
The role of nucleoplasmin in chromatin assembly and disassembly.
  Journal
Philos. Trans. R. Soc. Lond. B. Biol. Sci. 339 (1993) 263-9; discussion 268-9.
Reference
2  [PMID:8016655]
  Authors
Cote J, Quinn J, Workman JL, Peterson CL.
  Title
Stimulation of GAL4 derivative binding to nucleosomal DNA by the yeast SWI/SNF complex.
  Journal
Science. 265 (1994) 53-60.
Reference
3  [PMID:8798787]
  Authors
Ito T, Tyler JK, Bulger M, Kobayashi R, Kadonaga JT.
  Title
ATP-facilitated chromatin assembly with a nucleoplasmin-like protein from Drosophila melanogaster.
  Journal
J. Biol. Chem. 271 (1996) 25041-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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