KEGG   ENZYME: 3.7.1.4Help
Entry
EC 3.7.1.4                  Enzyme                                 

Name
phloretin hydrolase;
lactase-phlorizin hydrolase
Class
Hydrolases;
Acting on carbon-carbon bonds;
In ketonic substances
BRITE hierarchy
Sysname
2',4,4',6'-tetrahydroxydehydrochalcone 1,3,5-trihydroxybenzenehydrolase
Reaction(IUBMB)
phloretin + H2O = phloretate + phloroglucinol [RN:R02901]
Reaction(KEGG)
Substrate
phloretin [CPD:C00774];
H2O [CPD:C00001]
Product
phloretate [CPD:C01744];
phloroglucinol [CPD:C02183]
Comment
Also hydrolyses other C-acylated phenols related to phloretin.
History
EC 3.7.1.4 created 1972
Reference
1  [PMID:5441377]
  Authors
Minamikawa T, Jayasankar NP, Bohm BA, Taylor IE, Towers GH.
  Title
An inducible hydrolase from Aspergillus niger, acting on carbon-carbon bonds, for phlorrhizin and other C-acylated phenols.
  Journal
Biochem. J. 116 (1970) 889-97.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37289-38-6

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