| Entry |
|
|---|
| Name |
2-hydroxymuconate-semialdehyde hydrolase;
2-hydroxy-6-oxohepta-2,4-dienoate hydrolase;
2-hydroxymuconic semialdehyde hydrolase;
HMSH;
HOD hydrolase |
|---|
| Class |
Hydrolases;
Acting on carbon-carbon bonds;
In ketonic substances
 |
|---|
| Sysname |
2-hydroxymuconate-semialdehyde formylhydrolase |
|---|
| Reaction(IUBMB) |
2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate
[RN:R02604] |
|---|
| Reaction(KEGG) |
R02604;
(other) R05296 R05362 R05865
 |
|---|
| Substrate |
2-hydroxymuconate semialdehyde [CPD:C00682];
H2O [CPD:C00001] |
|---|
| Product |
formate [CPD:C00058];
2-oxopent-4-enoate [CPD:C00596] |
|---|
| Pathway |
PATH: ec00362 Benzoate degradation via hydroxylation
PATH: ec00622 Toluene and xylene degradation
PATH: ec00627 1,4-Dichlorobenzene degradation
PATH: ec00629 Carbazole degradation
PATH: ec00643 Styrene degradation
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K10216 2-hydroxymuconate-semialdehyde hydrolase |
|---|
| Genes |
AZO: azo1968(xylF)
 |
|---|
| Structures |
PDB: 1IUN 1IUO 1IUP 1UK6 1UK7 1UK8 1UK9 1UKA 1UKB 2D0D |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:3481421]
Harayama S, Rekik M, Wasserfallen A, Bairoch A.
Evolutionary relationships between catabolic pathways for aromatics:
conservation of gene order and nucleotide sequences of catechol
oxidation genes of pWW0 and NAH7 plasmids.
Mol. Gen. Genet. 210 (1987) 241-7.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:4325686]
Sala-Trepat JM, Evans WC.
The meta cleavage of catechol by Azotobacter species.
4-Oxalocrotonate pathway.
Eur. J. Biochem. 20 (1971) 400-13.
Azotobacter sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.7.1.9
IUBMB Enzyme Nomenclature: 3.7.1.9
ExPASy - ENZYME nomenclature database: 3.7.1.9
UM-BBD (Biocatalysis/Biodegradation Database): 3.7.1.9
BRENDA, the Enzyme Database: 3.7.1.9
CAS: 54004-61-4 |
|---|
