| Entry |
|
|---|
| Name |
atrazine chlorohydrolase;
AtzA |
|---|
| Class |
Hydrolases;
Acting on halide bonds;
In carbon-halide compounds
 |
|---|
| Sysname |
atrazine chlorohydrolase |
|---|
| Reaction(IUBMB) |
atrazine + H2O =
4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + HCl
[RN:R05558] |
|---|
| Reaction(KEGG) |
R05558
 |
|---|
| Substrate |
atrazine [CPD:C06551];
H2O [CPD:C00001] |
|---|
| Product |
4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine
[CPD:C06552];
HCl [CPD:C01327] |
|---|
| Comment |
Involved in the degradation of the herbicide atrazine,
2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine, in
bacteria. |
|---|
| Pathway |
PATH: ec00791 Atrazine degradation
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K05394 atrazine chlorohydrolase |
|---|
| Genes |
CVI: CV_1032
BUR: Bcep18194_B2475
EBA: ebA911
DAR: Daro_1229
TBD: Tbd_0947
MFA: Mfla_1577
DDE: Dde_1812
RHA: RHA1_ro04512(atzA)
HWA: HQ2047A(trzA)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:7574646]
de Souza ML, Wackett LP, Boundy-Mills KL, Mandelbaum RT, Sadowsky
MJ.
Cloning, characterization, and expression of a gene region from
Pseudomonas sp. strain ADP involved in the dechlorination of
atrazine.
Appl. Environ. Microbiol. 61 (1995) 3373-8.
Pseudomonas sp. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:8759853]
de Souza ML, Sadowsky MJ, Wackett LP.
Atrazine chlorohydrolase from Pseudomonas sp. strain ADP: gene
sequence, enzyme purification, and protein characterization.
J. Bacteriol. 178 (1996) 4894-900.
Pseudomonas sp. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 3.8.1.8
IUBMB Enzyme Nomenclature: 3.8.1.8
ExPASy - ENZYME nomenclature database: 3.8.1.8
UM-BBD (Biocatalysis/Biodegradation Database): 3.8.1.8
BRENDA, the Enzyme Database: 3.8.1.8
CAS: 168680-16-8 |
|---|
