KEGG   ENZYME: 4.1.1.29Help
Entry
EC 4.1.1.29                 Enzyme                                 
Name
sulfinoalanine decarboxylase;
cysteine-sulfinate decarboxylase;
L-cysteinesulfinic acid decarboxylase;
cysteine-sulfinate decarboxylase;
CADCase/CSADCase;
CSAD;
cysteic decarboxylase;
cysteinesulfinic acid decarboxylase;
cysteinesulfinate decarboxylase;
sulfoalanine decarboxylase;
3-sulfino-L-alanine carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)
Reaction(IUBMB)
3-sulfino-L-alanine = hypotaurine + CO2 [RN:R02466]
Reaction(KEGG)
R02466;
(other) R01682
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Substrate
3-sulfino-L-alanine [CPD:C00606]
Product
hypotaurine [CPD:C00519];
CO2 [CPD:C00011]
Comment
A pyridoxal-phosphate protein. Also acts on L-cysteate. The 1992 edition of the Enzyme List erroneously gave the name sulfoalanine decarboxylase to this enzyme.
Pathway
Taurine and hypotaurine metabolism
Metabolic pathways
Orthology
K01594  
sulfinoalanine decarboxylase
Genes
HSA: 
51380(CSAD)
PTR: 
100612110(CSAD)
PPS: 
100990133(CSAD)
PON: 
100443784(CSAD)
MCC: 
701290(CSAD)
MMU: 
246277(Csad)
RNO: 
60356(Csad)
CFA: 
486510(CSAD)
AML: 
100473959(CSAD)
FCA: 
101099732(CSAD)
BTA: 
516241(CSAD)
SSC: 
100626403
ECB: 
100061989(CSAD)
MDO: 
100010648(CSAD)
SHR: 
100914401(CSAD)
GGA: 
426184(CSAD)
TGU: 
100231277
ACS: 
100555254
XTR: 
100486477(csad)
DRE: 
492476(csad)
TRU: 
101076940
OLA: 
101174915
BFO: 
BRAFLDRAFT_58194
SPU: 
575490(csad)
DME: 
Dmel_CG5618
DPO: 
Dpse_GA19009
SYG: 
sync_1564
 » show all
Taxonomy
Reference
1  [PMID:236774]
  Authors
Guion-Rain M-C, Portemer C, Chatagner F.
  Title
Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties.
  Journal
Biochim. Biophys. Acta. 384 (1975) 265-76.
  Organism
Rattus norvegicus [GN:rno]
Reference
2  [PMID:14159288]
  Authors
JACOBSEN JG, THOMAS LL, SMITH LH Jr.
  Title
PROPERTIES AND DISTRIBUTION OF MAMMALIAN L-CYSTEINE SULFINATE CARBOXY-LYASES.
  Journal
Biochim. Biophys. Acta. 85 (1964) 103-16.
  Organism
Rattus norvegicus [GN:rno], Canis familiaris [GN:cfa], Gallus gallus [GN:gga], Felis catus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
62213-10-9
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