KEGG   ENZYME: 4.1.1.29Help
Entry
EC 4.1.1.29                 Enzyme                                 

Name
sulfinoalanine decarboxylase;
cysteine-sulfinate decarboxylase;
L-cysteinesulfinic acid decarboxylase;
cysteine-sulfinate decarboxylase;
CADCase/CSADCase;
CSAD;
cysteic decarboxylase;
cysteinesulfinic acid decarboxylase;
cysteinesulfinate decarboxylase;
sulfoalanine decarboxylase;
3-sulfino-L-alanine carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming)
Reaction(IUBMB)
3-sulfino-L-alanine = hypotaurine + CO2 [RN:R02466]
Reaction(KEGG)
R02466;
(other) R01682
Show
Substrate
3-sulfino-L-alanine [CPD:C00606]
Product
hypotaurine [CPD:C00519];
CO2 [CPD:C00011]
Comment
A pyridoxal-phosphate protein. Also acts on L-cysteate. The 1992 edition of the Enzyme List erroneously gave the name sulfoalanine decarboxylase to this enzyme.
History
EC 4.1.1.29 created 1961, deleted 1972, reinstated 1976, modified 1983, modified 1999
Pathway
Taurine and hypotaurine metabolism
Metabolic pathways
Orthology
K01594  
sulfinoalanine decarboxylase
Genes
HSA: 
51380(CSAD)
PTR: 
100612110(CSAD)
PPS: 
100990133(CSAD)
GGO: 
PON: 
100443784(CSAD)
NLE: 
100598252(CSAD)
MCC: 
701290(CSAD)
MCF: 
102139620(CSAD)
CJC: 
100402142(CSAD)
MMU: 
246277(Csad)
RNO: 
60356(Csad)
CGE: 
NGI: 
103738454(Csad)
HGL: 
101721018(Csad)
OCU: 
100355612(CSAD)
TUP: 
102467909(CSAD)
CFA: 
486510(CSAD)
AML: 
100473959(CSAD)
UMR: 
103675520(CSAD)
FCA: 
101099732(CSAD)
PTG: 
102952351(CSAD)
BTA: 
516241(CSAD)
BOM: 
102286213(CSAD)
PHD: 
102336000(CSAD)
CHX: 
102180652(CSAD)
OAS: 
SSC: 
100515377(CSAD)
CFR: 
102523405(CSAD)
BACU: 
103010783(CSAD)
LVE: 
103078140(CSAD)
ECB: 
100061989(CSAD)
MYB: 
102260711(CSAD)
MYD: 
102754688(CSAD)
PALE: 
102896743(CSAD)
MDO: 
100010648(CSAD)
SHR: 
100914401(CSAD)
GGA: 
426184(CSAD)
TGU: 
FAB: 
101806145(CSAD)
PHI: 
FPG: 
101918958(CSAD)
FCH: 
ASN: 
102374498(CSAD)
AMJ: 
102571615(CSAD)
PSS: 
102449282(CSAD)
CMY: 
102929538(CSAD)
ACS: 
100555254(csad)
PBI: 
103066892(CSAD)
XTR: 
100486477(csad)
DRE: 
492476(csad)
TRU: 
MZE: 
OLA: 
XMA: 
LCM: 
CMK: 
103189933(csad)
BFO: 
CIN: 
448952(csd)
SPU: 
575490(csad)
DME: 
DPO: 
DER: 
DPE: 
DSE: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
LGI: 
GTT: 
SYG: 
 » show all
Taxonomy
Reference
1  [PMID:236774]
  Authors
Guion-Rain M-C, Portemer C, Chatagner F.
  Title
Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties.
  Journal
Biochim. Biophys. Acta. 384 (1975) 265-76.
Reference
2  [PMID:14159288]
  Authors
JACOBSEN JG, THOMAS LL, SMITH LH Jr.
  Title
PROPERTIES AND DISTRIBUTION OF MAMMALIAN L-CYSTEINE SULFINATE CARBOXY-LYASES.
  Journal
Biochim. Biophys. Acta. 85 (1964) 103-16.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
62213-10-9

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