| Entry |
|
|---|
| Name |
sulfinoalanine decarboxylase;
cysteine-sulfinate decarboxylase;
L-cysteinesulfinic acid decarboxylase;
cysteine-sulfinate decarboxylase;
CADCase/CSADCase;
CSAD;
cysteic decarboxylase;
cysteinesulfinic acid decarboxylase;
cysteinesulfinate decarboxylase;
sulfoalanine decarboxylase;
3-sulfino-L-alanine carboxy-lyase |
|---|
| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
 |
|---|
| Sysname |
3-sulfino-L-alanine carboxy-lyase (hypotaurine-forming) |
|---|
| Reaction(IUBMB) |
3-sulfino-L-alanine = hypotaurine + CO2 [RN:R02466] |
|---|
| Reaction(KEGG) |
R02466;
(other) R01682
 |
|---|
| Substrate |
3-sulfino-L-alanine [CPD:C00606] |
|---|
| Product |
hypotaurine [CPD:C00519];
CO2 [CPD:C00011] |
|---|
| Cofactor |
Pyridoxal phosphate [CPD:C00018] |
|---|
| Comment |
A pyridoxal-phosphate protein. Also acts on L-cysteate. The 1992
edition of the Enzyme List erroneously gave the name sulfoalanine
decarboxylase to this enzyme. |
|---|
| Pathway |
ec00430 Taurine and hypotaurine metabolism
ec01100 Metabolic pathways |
|---|
| Orthology |
K01594 sulfinoalanine decarboxylase |
|---|
| Genes |
HSA: 51380(CSAD)
MCC: 701290(CSAD)
MMU: 246277(Csad)
RNO: 60356(Csad)
SSC: 100157951
ECB: 100061989
MDO: 100010648
DRE: 492476(csad)
SPU: 575490
DME: Dmel_CG5618
DPO: Dpse_GA19009
SYG: sync_1564
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:236774]
Guion-Rain M-C, Portemer C, Chatagner F.
Rat liver cysteine sulfinate decarboxylase: purification, new
appraisal of the molecular weight and determination of catalytic
properties.
Biochim. Biophys. Acta. 384 (1975) 265-76.
Rattus norvegicus [GN:rno] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:14159288]
JACOBSEN JG, THOMAS LL, SMITH LH Jr.
PROPERTIES AND DISTRIBUTION OF MAMMALIAN L-CYSTEINE SULFINATE
CARBOXY-LYASES.
Biochim. Biophys. Acta. 85 (1964) 103-16.
Rattus norvegicus [GN:rno], Canis familiaris [GN:cfa], Gallus gallus
[GN:gga], Felis catus |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.1.1.29
IUBMB Enzyme Nomenclature: 4.1.1.29
ExPASy - ENZYME nomenclature database: 4.1.1.29
BRENDA, the Enzyme Database: 4.1.1.29
CAS: 62213-10-9 |
|---|
