KEGG   ENZYME: 4.1.1.74Help
Entry
EC 4.1.1.74                 Enzyme                                 

Name
indolepyruvate decarboxylase;
indol-3-yl-pyruvate carboxy-lyase;
3-(indol-3-yl)pyruvate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]
Reaction(IUBMB)
3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO2 [RN:R01974]
Reaction(KEGG)
Substrate
3-(indol-3-yl)pyruvate [CPD:C00331]
Product
2-(indol-3-yl)acetaldehyde [CPD:C00637];
CO2 [CPD:C00011]
Comment
Thiamine diphosphate- and Mg2+-dependent. More specific than EC 4.1.1.1 pyruvate decarboxylase
History
EC 4.1.1.74 created 1999
Pathway
Tryptophan metabolism
Metabolic pathways
Orthology
K04103  
indolepyruvate decarboxylase
Genes
STY: 
STT: 
STM: 
SPT: 
SEK: 
SPQ: 
SEI: 
SEC: 
SCH_2408(dciP)
SEH: 
SEE: 
SEW: 
SEA: 
SEG: 
SET: 
SES: 
ENT: 
ESC: 
ESA: 
CSJ: 
CDM: 
CMW: 
CTU: 
CTU_29970(ipdC)
KPN: 
KPU: 
KPE: 
KPK_1400(ipdC)
KMI: 
CKO: 
CRO: 
CNT: 
CEM: 
CEN: 
CED: 
PGE: 
YEN: 
YE1222(ipdC)
YEP: 
YEY: 
YEW: 
CH47_624(ipdC)
YET: 
YEF: 
YEE: 
YRO: 
SPE: 
SMAF: 
SRZ: 
RAH: 
ECA: 
ECA3605(ipdC)
PCT: 
DDC: 
ETA: 
ETA_11130(ipdC)
EAM: 
EAMY_2469(pdc3)
EAY: 
EAM_2375(ipdC)
EBI: 
EbC_32520(ipdC)
PAM: 
PANA_2745(ipdC)
PLF: 
PAO: 
PANP: 
PMR: 
PMI0845(ipdC)
EIC: 
ETR: 
PEN: 
SWP: 
FTU: 
FTT_1744c(ipdC)
FTF: 
FTF1744c(ipdC)
FTW: 
FTL: 
FTM: 
FTM_1730(idpC)
FTN: 
FTN_0116(ipdC)
FPH: 
HCH: 
RFR: 
EBA: 
ebA6545(pdc)
TMZ: 
APP: 
DVM: 
DDE: 
DMA: 
DSA: 
DPS: 
SMD: 
RET: 
REC: 
BRA: 
BRADO7016(ipdC)
BBT: 
BBta_0512(ipdC)
RPA: 
RPA3116(ipdC)
RPB: 
RPD: 
RPT: 
SNO: 
BID: 
RRU: 
BCG: 
BCX: 
BTL: 
BWE: 
MPE: 
MYPE6890(MYPE6890)
CAR: 
FRI: 
KRA: 
SAQ: 
SYG: 
SYX: 
TSA: 
CPI: 
FJO: 
MAC: 
MA_0594(ipdC)
MBA: 
 » show all
Taxonomy
Reference
1  [PMID:7766676]
  Authors
Koga J.
  Title
Structure and function of indolepyruvate decarboxylase, a key enzyme in indole-3-acetic acid biosynthesis.
  Journal
Biochim. Biophys. Acta. 1249 (1995) 1-13.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9074-92-4

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