| Entry |
|
|---|
| Name |
mandelonitrile lyase;
hydroxynitrile lyase;
(R)-oxynitrilase;
oxynitrilase;
D-oxynitrilase;
D-alpha-hydroxynitrile lyase;
mandelonitrile benzaldehyde-lyase |
|---|
| Class |
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
 |
|---|
| Sysname |
mandelonitrile benzaldehyde-lyase (cyanide-forming) |
|---|
| Reaction(IUBMB) |
mandelonitrile = cyanide + benzaldehyde [RN:R01767] |
|---|
| Reaction(KEGG) |
R01767;
(other) R01409 R02811
 |
|---|
| Substrate |
mandelonitrile [CPD:C00561] |
|---|
| Product |
cyanide [CPD:C00177];
benzaldehyde [CPD:C00261] |
|---|
| Cofactor |
Flavin [CPD:C00176];
Flavoprotein [CPD:C06411] |
|---|
| Comment |
A variety of enzymes from different sources and with different
properties. Some are flavoproteins, others are not. Active towards a
number of aromatic and aliphatic hydroxynitriles (cyanohydrins). |
|---|
| Pathway |
ec00460 Cyanoamino acid metabolism
ec01100 Metabolic pathways |
|---|
| Orthology |
K08248 mandelonitrile lyase |
|---|
| Genes |
ATH: AT1G73050
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13970146]
BECKER W, BENTHIN U, ESCHENHOF E, PFEIL E.
[On the knowledge of cyanhydrin synthesis. II. Purification and
properties of hydroxynitrilase from bitter almonds (Prunus communis
Stokes)]
Biochem. Z. 337 (1963) 156-66.
Prunus dulcis |
|---|
Reference
Authors
Title
Journal
|
2
Becker, W. and Pfeil, E.
Die Darstellung kristallisierter Oxynitrilase aus bitteren Mandeln
(Prunus comm. Stks).
Naturwissenschaften 51 (1964) 193. |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:6803611]
Gross M, Jacobs GH, Poulton JE.
A rapid and sensitive spectrophotometric assay for prunasin
hydrolase activity employing purified mandelonitrile lyase.
Anal. Biochem. 119 (1982) 25-30.
Prunus dulcis |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:3777939]
Xu LL, Singh BK, Conn EE.
Purification and characterization of mandelonitrile lyase from
Prunus lyonii.
Arch. Biochem. Biophys. 250 (1986) 322-8.
Prunus lyonii |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:3717954]
Yemm RS, Poulton JE.
Isolation and characterization of multiple forms of mandelonitrile
lyase from mature black cherry (Prunus serotina Ehrh.) seeds.
Arch. Biochem. Biophys. 247 (1986) 440-5.
Prunus serotina |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 4.1.2.10
IUBMB Enzyme Nomenclature: 4.1.2.10
ExPASy - ENZYME nomenclature database: 4.1.2.10
BRENDA, the Enzyme Database: 4.1.2.10
CAS: 9024-43-5 |
|---|
