KEGG   ENZYME: 4.1.2.12Help
Entry
EC 4.1.2.12                 Enzyme                                 

Name
2-dehydropantoate aldolase;
ketopantoaldolase;
2-dehydropantoate formaldehyde-lyase
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
BRITE hierarchy
Sysname
2-dehydropantoate formaldehyde-lyase (3-methyl-2-oxobutanoate-forming)
Reaction(IUBMB)
2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde [RN:R01216]
Reaction(KEGG)
Substrate
2-dehydropantoate [CPD:C00966]
Product
3-methyl-2-oxobutanoate [CPD:C00141];
formaldehyde [CPD:C00067]
History
EC 4.1.2.12 created 1965, modified 2002
Reference
1  [PMID:13475336]
  Authors
McINTOSH EN, PURKO M, WOOD WA.
  Title
Ketopantoate formation by a hydroxy-methylation enzyme from Escherichia coli.
  Journal
J. Biol. Chem. 228 (1957) 499-510.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9024-51-5

DBGET integrated database retrieval system