KEGG   ENZYME: 4.1.2.49Help
Entry
EC 4.1.2.49                 Enzyme                                 

Name
L-allo-threonine aldolase
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
BRITE hierarchy
Sysname
L-allo-threonine acetaldehyde-lyase (glycine-forming)
Reaction(IUBMB)
L-allo-threonine = glycine + acetaldehyde [RN:R06171]
Reaction(KEGG)
Substrate
L-allo-threonine [CPD:C05519]
Product
glycine [CPD:C00037];
acetaldehyde [CPD:C00084]
Comment
Requires pyridoxal phosphate. This enzyme, characterized from the bacterium Aeromonas jandaei, is specific for L-allo-threonine and can not act on either L-threonine or L-serine. Different from EC 4.1.2.5, L-threonine aldolase, and EC 4.1.2.48, low-specificity L-threonine aldolase. A previously listed enzyme with this name, EC 4.1.2.6, was deleted in 1971 after it was found to be identical to EC 2.1.2.1, glycine hydroxymethyltransferase.
History
EC 4.1.2.49 created 2011
Pathway
Glycine, serine and threonine metabolism
Metabolic pathways
Reference
1  [PMID:9228760]
  Authors
Kataoka M, Wada M, Nishi K, Yamada H, Shimizu S
  Title
Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39.
  Journal
FEMS. Microbiol. Lett. 151 (1997) 245-8.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system