KEGG   ENZYME: 4.1.2.49Help
Entry
EC 4.1.2.49                 Enzyme                                 

Name
L-allo-threonine aldolase
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
BRITE hierarchy
Sysname
L-allo-threonine acetaldehyde-lyase (glycine-forming)
Reaction(IUBMB)
L-allo-threonine = glycine + acetaldehyde [RN:R06171]
Reaction(KEGG)
Substrate
L-allo-threonine [CPD:C05519]
Product
glycine [CPD:C00037];
acetaldehyde [CPD:C00084]
Comment
Requires pyridoxal phosphate. This enzyme, characterized from the bacterium Aeromonas jandaei, is specific for L-allo-threonine and can not act on either L-threonine or L-serine. Different from EC 4.1.2.5, L-threonine aldolase, and EC 4.1.2.48, low-specificity L-threonine aldolase. A previously listed enzyme with this name, EC 4.1.2.6, was deleted in 1971 after it was found to be identical to EC 2.1.2.1, glycine hydroxymethyltransferase.
History
EC 4.1.2.49 created 2011
Pathway
ec00260  Glycine, serine and threonine metabolism
ec01100  Metabolic pathways
Orthology
K20801  L-allo-threonine aldolase
Genes
AHA: AHA_1795
AHY: AHML_09870
AHD: AI20_10070
AHR: V428_10130
AHP: V429_10135
AHJ: V469_13360
AHH: RY45_09770
AHI: VU14_13575
ASA: ASA_1753(ltaA)
AEO: O23A_p1041
AVR: B565_2324
AMED: B224_1834
ASR: WL1483_125(ltaA)
 » show all
Taxonomy
Reference
1  [PMID:9228760]
  Authors
Kataoka M, Wada M, Nishi K, Yamada H, Shimizu S
  Title
Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39.
  Journal
FEMS. Microbiol. Lett. 151 (1997) 245-8.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.1.2.49
IUBMB Enzyme Nomenclature: 4.1.2.49
ExPASy - ENZYME nomenclature database: 4.1.2.49
BRENDA, the Enzyme Database: 4.1.2.49

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