KEGG   ENZYME: 4.1.3.14Help
Entry
EC 4.1.3.14                 Enzyme                                 

Name
L-erythro-3-hydroxyaspartate aldolase;
L-erythro-beta-hydroxyaspartate aldolase;
L-erythro-beta-hydroxyaspartate glycine-lyase;
erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase
Class
Lyases;
Carbon-carbon lyases;
Oxo-acid-lyases
BRITE hierarchy
Sysname
L-erythro-3-hydroxy-aspartate glyoxylate-lyase (glycine-forming)
Reaction(IUBMB)
L-erythro-3-hydroxy-aspartate = glycine + glyoxylate [RN:R00478]
Reaction(KEGG)
Substrate
L-erythro-3-hydroxy-aspartate
Product
glycine [CPD:C00037];
glyoxylate [CPD:C00048]
Comment
A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Paracoccus denitrificans NCIMB 8944, is strictly specific for the L-erythro stereoisomer of 3-hydroxyaspartate. Different from EC 4.1.3.41, erythro-3-hydroxy-D-aspartate aldolase. Requires a divalent cation.
History
EC 4.1.3.14 created 1972, modified 2011
Reference
1  [PMID:14194868]
  Authors
GIBBS RG, MORRIS JG.
  Title
ASSAY AND PROPERTIES OF BETA-HYDROXYASPARTATE ALDOLASE FROM MICROCOCCUS DENITRIFICANS.
  Journal
Biochim. Biophys. Acta. 85 (1964) 501-3.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37290-64-5

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