KEGG   ENZYME: 4.1.3.32Help
Entry
EC 4.1.3.32                 Enzyme                                 

Name
2,3-dimethylmalate lyase;
2,3-dimethylmalate pyruvate-lyase;
(2R,3S)-2,3-dimethylmalate pyruvate-lyase
Class
Lyases;
Carbon-carbon lyases;
Oxo-acid-lyases
BRITE hierarchy
Sysname
(2R,3S)-2,3-dimethylmalate pyruvate-lyase (propanoate-forming)
Reaction(IUBMB)
(2R,3S)-2,3-dimethylmalate = propanoate + pyruvate [RN:R01355]
Reaction(KEGG)
Substrate
(2R,3S)-2,3-dimethylmalate [CPD:C03652]
Product
propanoate [CPD:C00163];
pyruvate [CPD:C00022]
History
EC 4.1.3.32 created 1981
Pathway
Nicotinate and nicotinamide metabolism
Microbial metabolism in diverse environments
Orthology
K20454  
2,3-dimethylmalate lyase
Genes
HCO: 
BPAR: 
BBR: 
BB0718(bcpA)
BBH: 
BBX: 
ACK: 
LIH: 
DTO: 
BBT: 
ABS: 
ABQ: 
CAH: 
DGI: 
DOR: 
SAY: 
TPY_1957(prpB)
SAP: 
TEP: 
TAE: 
TNR: 
NTH: 
RAV: 
BSD: 
MMAR: 
AMQ: 
PDX: 
PSEA: 
PSEE: 
PSEQ: 
PECQ: 
ACO: 
TLI: 
AMO: 
 » show all
Taxonomy
Reference
1  [PMID:527937]
  Authors
Pirzer P, Lill U, Eggerer H.
  Title
Nicotinic acid metabolism. 2,3-Dimethylmalate lyase.
  Journal
Hoppe. Seylers. Z. Physiol. Chem. 360 (1979) 1693-702.
  Sequence
Reference
2  [PMID:16894175]
  Authors
Alhapel A, Darley DJ, Wagener N, Eckel E, Elsner N, Pierik AJ.
  Title
Molecular and functional analysis of nicotinate catabolism in Eubacterium barkeri.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 12341-6.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
73562-28-4

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