KEGG   ENZYME: 4.2.1.124Help
Entry
EC 4.2.1.124                Enzyme                                 

Name
arabidiol synthase;
PEN1 (gene name);
(S)-squalene-2,3-epoxide hydro-lyase (arabidiol forming)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene hydro-lyase (arabidiol forming)
Reaction(IUBMB)
arabidiol = (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O [RN:R09700]
Reaction(KEGG)
Substrate
arabidiol [CPD:C19828]
Product
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054];
H2O [CPD:C00001]
Comment
The reaction occurs in the reverse direction.
History
EC 4.2.1.124 created 2011
Pathway
Sesquiterpenoid and triterpenoid biosynthesis
Biosynthesis of secondary metabolites
Orthology
K15823  
arabidiol synthase
Genes
ATH: 
AT4G15340(PEN1)
Taxonomy
Reference
1  [PMID:16774269]
  Authors
Xiang T, Shibuya M, Katsube Y, Tsutsumi T, Otsuka M, Zhang H, Masuda K, Ebizuka Y
  Title
A new triterpene synthase from Arabidopsis thaliana produces a tricyclic triterpene with two hydroxyl groups.
  Journal
Org. Lett. 8 (2006) 2835-8.
  Sequence
[ath:AT4G15340]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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