KEGG   ENZYME: 4.2.1.131Help
Entry
EC 4.2.1.131                Enzyme                                 

Name
carotenoid 1,2-hydratase;
CrtC
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming)
Reaction(IUBMB)
(1) 1-hydroxy-1,2-dihydrolycopene = lycopene + H2O [RN:R07519];
(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene = 1-hydroxy-1,2-dihydrolycopene + H2O [RN:R09790]
Reaction(KEGG)
Substrate
1-hydroxy-1,2-dihydrolycopene [CPD:C19795];
1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene [CPD:C19894]
Product
lycopene [CPD:C05432];
H2O [CPD:C00001];
1-hydroxy-1,2-dihydrolycopene [CPD:C19795]
Comment
In Rubrivivax gelatinosus [1] and Thiocapsa roseopersicina [2] both products are formed, whereas Rhodobacter capsulatus [1] only gives 1-hydroxy-1,2-dihydrolycopene. Also acts on neurosporene giving 1-hydroxy-1,2-dihydroneurosporene with both organism but 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene only with Rubrivivax gelatinosus.
History
EC 4.2.1.131 created 2011
Pathway
Carotenoid biosynthesis
Metabolic pathways
Orthology
K09844  
carotenoid 1,2-hydratase
Genes
ALV: 
TVI: 
TMB: 
MPUR: 
HHA: 
HHC: 
PDQ: 
LIM: 
LIH: 
RGE: 
RGE_33580(crtC)
RBN: 
RDP: 
MXA: 
MFU: 
MSD: 
MYM: 
CCX: 
SUR: 
AGE: 
SCL: 
sce0584(crtC)
SCU: 
CCRO: 
BRA: 
BRADO1613(crtC)
BBT: 
BBta_6442(crtC)
BRS: 
S23_19130(crtC)
AOL: 
RPA: 
RPA1517(crtC)
RPB: 
RPC: 
RPD: 
RPE: 
RPT: 
RPX: 
MEX: 
MEA: 
MDI: 
METDI3491(crtC)
MCH: 
MRD: 
MET: 
MPO: 
MOR: 
META: 
MAQU: 
MSL: 
RVA: 
BSB: 
RSP: 
RSP_0267(crtC)
RSH: 
RSQ: 
RSK: 
RCP: 
JAN: 
Jann_0184(crtC)
RDE: 
RD1_0116(crtC)
RLI: 
DSH: 
Dshi_3512(crtC)
RED: 
PTP: 
RSU: 
SPHI: 
SSAN: 
CIJ: 
AMV: 
RRU: 
RRF: 
RPM: 
CTM: 
IPA: 
CTE: 
CT0301(crtC)
CPC: 
CCH: 
CPH: 
CPB: 
CLI: 
PVI: 
PLT: 
PPH: 
PAA: 
CTS: 
 » show all
Taxonomy
Reference
1  [PMID:12745254]
  Authors
Steiger S, Mazet A, Sandmann G
  Title
Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus.
  Journal
Arch. Biochem. Biophys. 414 (2003) 51-8.
  Sequence
Reference
2  [PMID:21590288]
  Authors
Hiseni A, Arends IW, Otten LG
  Title
Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina.
  Journal
Appl. Microbiol. Biotechnol. 91 (2011) 1029-36.
  Sequence
[rge:RGE_33580] [ag:AAP59035]
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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