KEGG   ENZYME: 4.2.1.131Help
Entry
EC 4.2.1.131                Enzyme                                 
Name
carotenoid 1,2-hydratase;
CrtC
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming)
Reaction(IUBMB)
(1) 1-hydroxy-1,2-dihydrolycopene = lycopene + H2O [RN:R07519];
(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene = 1-hydroxy-1,2-dihydrolycopene + H2O [RN:R09790]
Reaction(KEGG)
Substrate
1-hydroxy-1,2-dihydrolycopene [CPD:C19795];
1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene [CPD:C19894]
Product
lycopene [CPD:C05432];
H2O [CPD:C00001];
1-hydroxy-1,2-dihydrolycopene [CPD:C19795]
Comment
In Rubrivivax gelatinosus [1] and Thiocapsa roseopersicina [2] both products are formed, whereas Rhodobacter capsulatus [1] only gives 1-hydroxy-1,2-dihydrolycopene. Also acts on neurosporene giving 1-hydroxy-1,2-dihydroneurosporene with both organism but 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene only with Rubrivivax gelatinosus.
Pathway
Carotenoid biosynthesis
Orthology
K09844  
carotenoid 1,2-hydratase
Genes
ALV: 
TVI: 
TMB: 
HHA: 
RGE: 
RGE_33580(crtC)
MXA: 
MFU: 
MSD: 
CCX: 
SUR: 
SCL: 
sce0584(crtC)
BRA: 
BRADO1613(crtC)
BBT: 
BBta_6442(crtC)
BRS: 
S23_19130(crtC)
RPA: 
RPA1517(crtC)
RPB: 
RPB_4006
RPC: 
RPC_1288
RPD: 
RPD_3761
RPE: 
RPE_1320
RPT: 
Rpal_1705
RPX: 
Rpdx1_4003
AOL: 
S58_59230
MEX: 
Mext_2725
MEA: 
Mex_1p2922
MDI: 
METDI3491(crtC)
MCH: 
Mchl_2952
MRD: 
Mrad2831_2823
MET: 
M446_3692
MPO: 
Mpop_2847
MSL: 
Msil_2047
RVA: 
Rvan_0206
BSB: 
Bresu_3049
RSP: 
RSP_0267(ctrC)
RSH: 
Rsph17029_1911
RSQ: 
Rsph17025_2041
RSK: 
RSKD131_1594
RCP: 
RCAP_rcc00682(crtC)
JAN: 
Jann_0184
RDE: 
RD1_0116(crtC)
RLI: 
RLO149_p940110(crtC)
DSH: 
Dshi_3512(crtC)
AMV: 
ACMV_18840(crtC)
RRU: 
Rru_A2985
RRF: 
F11_15290
RPM: 
RSPPHO_02322(crtC)
CTM: 
Cabther_A0575
IPA: 
Isop_1565
CTE: 
CT0301(crtC)
CPC: 
Cpar_1736
CCH: 
Cag_0393
CPH: 
Cpha266_0428
CPB: 
Cphamn1_1988
CLI: 
Clim_0360
PVI: 
Cvib_1502
PLT: 
Plut_1720
PPH: 
Ppha_0465
PAA: 
Paes_1781
CTS: 
Ctha_1182
 » show all
Taxonomy
Reference
1  [PMID:12745254]
  Authors
Steiger S, Mazet A, Sandmann G
  Title
Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus.
  Journal
Arch. Biochem. Biophys. 414 (2003) 51-8.
Reference
2  [PMID:21590288]
  Authors
Hiseni A, Arends IW, Otten LG
  Title
Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina.
  Journal
Appl. Microbiol. Biotechnol. 91 (2011) 1029-36.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
DBGET integrated database retrieval system