KEGG   ENZYME: 4.2.1.146Help
Entry
EC 4.2.1.146                Enzyme                                 

Name
L-galactonate dehydratase;
LGD1
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
L-galactonate hydro-lyase (2-dehydro-3-deoxy-L-galactonate-forming)
Reaction(IUBMB)
L-galactonate = 2-dehydro-3-deoxy-L-galactonate + H2O [RN:R10532]
Reaction(KEGG)
Substrate
L-galactonate [CPD:C15930]
Product
2-dehydro-3-deoxy-L-galactonate [CPD:C20680];
H2O [CPD:C00001]
Comment
The enzyme takes part in a D-galacturonate degradation pathway in the fungi Trichoderma reesei (Hypocrea jecorina) and Aspergillus niger.
History
EC 4.2.1.146 created 2013
Pathway
Pentose and glucuronate interconversions
Metabolic pathways
Orthology
K18102  
L-galactonate dehydratase
Genes
PPA: 
PGU: 
CTEN: 
NCR: 
NTE: 
NEUTE1DRAFT131658(NEUTE1DRAFT_131658)
SMP: 
PAN: 
TTT: 
MTM: 
CTHR: 
MGR: 
TMN: 
FGR: 
FPU: 
NHE: 
TRE: 
MAW: 
MAJ: 
CMT: 
VAL: 
VDA: 
ELA: 
SSL: 
BFU: 
MBE: 
ANI: 
AFM: 
AOR: 
AOR_1_1124054(AO090011000654)
ANG: 
ANI_1_1784144(An16g05390)
AFV: 
ACT: 
NFI: 
PCS: 
ABE: 
TVE: 
PNO: 
PTE: 
BZE: 
BSC: 
BOR: 
ZTR: 
PFJ: 
BCOM: 
NPA: 
TML: 
TMS: 
 » show all
Taxonomy
Reference
1  [PMID:16879654]
  Authors
Kuorelahti S, Jouhten P, Maaheimo H, Penttila M, Richard P
  Title
L-galactonate dehydratase is part of the fungal path for D-galacturonic acid catabolism.
  Journal
Mol. Microbiol. 61 (2006) 1060-8.
  Sequence
Reference
2  [PMID:18768163]
  Authors
Martens-Uzunova ES, Schaap PJ
  Title
An evolutionary conserved d-galacturonic acid metabolic pathway operates across filamentous fungi capable of pectin degradation.
  Journal
Fungal. Genet. Biol. 45 (2008) 1449-57.
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

DBGET integrated database retrieval system