| Entry |
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| Name |
CDP-glucose 4,6-dehydratase;
cytidine diphosphoglucose oxidoreductase;
CDP-glucose 4,6-hydro-lyase
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| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
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| Sysname |
CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy-D-glucose-forming)
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| Reaction(IUBMB) |
CDP-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H2O [RN: R02426]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
CDP-4-dehydro-6-deoxy-D-glucose [CPD: C01219];
H2O [CPD: C00001]
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| Comment |
Requires bound NAD+.
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| Pathway |
| Amino sugar and nucleotide sugar metabolism | | Biosynthesis of secondary metabolites |
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| Orthology |
| CDP-glucose 4,6-dehydratase |
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| Genes |
STY: | | STT: | | SEX: | | STM: | | SEO: | | SEV: | | SEY: | | SEM: | | SEJ: | | SEB: | | SEF: | | SPT: | | SEK: | | SPQ: | | SEH: | | SHB: | | SEE: | | SEW: | | SEA: | | SED: | | SEG: | | SEL: | | SET: | | SENJ: | | YPK: | | YPA: | | YPN: | | YPM: | | YPP: | | YPZ: | | YPT: | | YPD: | | YPX: | | YPH: | | YPS: | | YPI: | | YPY: | | YPB: | | YEN: | | ECA: | | VFI: | | VAN: | | PPF: | | PPW: | | PPB: | | PPI: | | PPUU: | | PSP: | | PFL: | | PFO: | | PFE: | | AVN: | | SDN: | | PAT: | | PIN: | | LLO: | | TCX: | | MEJ: | | ALV: | | TVI: | | MPC: | | AHA: | | AFI: | | GPB: | | CVI: | | LHK: | | RPI: | | RPF: | | REH: | | CTI: | | BPS: | | BPM: | | BPL: | | BPD: | | BPZ: | | BPQ: | | BTE: | | BAC: | | BPX: | | PNE: | | BAV: | | RFR: | | POL: | | VEI: | | HAR: | | HSE: | | AZA: | | DAR: | | TMZ: | | DSU: | | TBD: | | SLT: | | GCA: | | BPRC: | | SUA: | | SKU: | | SULR: | | CJN: | | NSA: | | SUN: | | GSK: | | GUR: | | GLO: | | GBM: | | GEO: | | GEM: | | PCA: | | PPD: | | DVU: | | DVL: | | DVM: | | DVG: | | DDE: | | DDS: | | DDN: | | DAS: | | DBA: | | BBA: | | BBAT: | | BMX: | | DOL: | | SCL: | | SAT: | | PEL: | | PLA: | | SME: | | SMK: | | SMQ: | | SMX: | | SMI: | | SMEG: | | SMEL: | | RHI: | | SFD: | | AVI: | | RLE: | | RLT: | | RLG: | | BJA: | | BJU: | | BRS: | | RPA: | | RPE: | | AZC: | | MEX: | | MEA: | | MDI: | | MCH: | | MRD: | | MET: | | MPO: | | MNO: | | HMC: | | MSC: | | CAK: | | PZU: | | PGL: | | HBA: | | SPHM: | | ACR: | | AMV: | | RCE: | | RPM: | | AZL: | | APB: | | PGV: | | BSR: | | BSL: | | BSH: | | BSY: | | BSS: | | BST: | | BSO: | | BSN: | | BSQ: | | BSUB: | | BSX: | | BAO: | | BAY: | | BAQ: | | BYA: | | BAMP: | | BAML: | | BAZ: | | BQL: | | BXH: | | BQY: | | BAMI: | | BAE: | | BAL: | | BCE: | | BCA: | | BCZ: | | BCR: | | BCB: | | BCG: | | BCQ: | | BNC: | | BCER: | | BCY: | | BTB: | | BTT: | | BTC: | | BTF: | | BTM: | | BTG: | | BTI: | | BTN: | | BTHT: | | BPU: | | BJS: | | BBE: | | PJD: | | PPM: | | PMS: | | PMQ: | | PMW: | | CTH: | | CTX: | | CBK: | | CSH: | | CSO: | | CSR: | | DDH: | | DCA: | | DRU: | | SGY: | | DED: | | DEC: | | ELM: | | ESR: | | ESU: | | BPB: | | CLE: | | RHO: | | RBR: | | ROB: | | BPRM: | | BPRS: | | CHD: | | CKN: | | SSG: | | SRI: | | MIT: | | MIR: | | MIA: | | MMI: | | MLI: | | CCU: | | PUV: | | WCH: | | TBE: | | TAZ: | | TPI: | | LIL: | | LIE: | | LIC: | | BRM: | | BPJ: | | BPIP: | | BPW: | | BIP: | | ACA: | | ACM: | | GMA: | | TSA: | | TRS: | | SUS: | | CTM: | | BTH: | | BFR: | | BFS: | | BFG: | | BVU: | | BHL: | | PPN: | | PRU: | | ASH: | | HHY: | | DFE: | | LBY: | | FAE: | | FBR: | | COC: | | FBC: | | IPO: | | CAA: | | PSL: | | SACI: | | SYN: | | SYZ: | | SYY: | | SYT: | | SYS: | | SYQ: | | SYC: | | SYF: | | SYNE: | | MAR: | | CYP: | | CYH: | | AMR: | | CGC: | | CMP: | | NOP: | | PMM: | | PMC: | | PMF: | | PMJ: | | LEP: | | OAC: | | CEP: | | MIC: | | ARP: | | CPC: | | CAP: | | SAF: | | PMX: | | TYE: | | LFC: | | CNI: | | MAE: | | MPI: | | MPL: | |
» show all
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| Reference |
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| Authors |
Hey AE, Elbein AD. |
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| Title |
Biosynthesis of tyvelose. The purification and properties of cytidine diphosphate D-glucose oxidoreductase. |
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| Journal |
J. Biol. Chem. 241 (1966) 5473-8. |
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| Organism |
Salmonella typhi |
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| Reference |
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| Authors |
Matsuhashi S, Matsuhashi M, Brown JG, Strominger JL. |
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| Title |
Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. 3. Cytidine diphosphate D-glucose oxidoreductase. |
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| Journal |
J. Biol. Chem. 241 (1966) 4283-7. |
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| Organism |
Pasteurella pseudotuberculosis |
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| Reference |
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| Authors |
Melo A, Elliott WH, Glaser L. |
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| Title |
The mechanism of 6-deoxyhexose synthesis. I. Intramolecular hydrogen transfer catalyzed by deoxythymidine diphosphate D-glucose oxidoreductase. |
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| Journal |
J. Biol. Chem. 243 (1968) 1467-74. |
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| Organism |
Salmonella typhimurium LT2 [GN: stm] |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 37259-55-5 |
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