KEGG   ENZYME: 4.2.1.57Help
Entry
EC 4.2.1.57                 Enzyme                                 

Name
isohexenylglutaconyl-CoA hydratase;
3-hydroxy-3-isohexenylglutaryl-CoA-hydrolase;
isohexenylglutaconyl coenzyme A hydratase;
beta-isohexenylglutaconyl-CoA-hydratase;
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA hydro-lyase [3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA-forming]
Reaction(IUBMB)
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H2O [RN:R03493]
Reaction(KEGG)
Substrate
3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA [CPD:C04675]
Product
3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA [CPD:C01291];
H2O [CPD:C00001]
Comment
Also acts on dimethylacryloyl-CoA and farnesoyl-CoA.
History
EC 4.2.1.57 created 1972
Pathway
Geraniol degradation
Orthology
K13779  
isohexenylglutaconyl-CoA hydratase
Genes
PAE: 
PA2890(atuE)
PAEV: 
PAEI: 
PAU: 
PAP: 
PAG: 
PAF: 
PNC: 
PAEB: 
PDK: 
PSG: 
PRP: 
PAEP: 
PAER: 
PAEM: 
PAEL: 
PAES: 
PAEU: 
PAEG: 
PAEC: 
PAEO: 
PMY: 
PMK: 
PRE: 
PPSE: 
PALC: 
PCQ: 
PcP3B5_19980(echA8_1)
PFL: 
PFL_4198(atuE)
PPRC: 
PPRO: 
PPC_4295(atuE)
PFO: 
PFS: 
PFC: 
PFN: 
PFW: 
PFB: 
PFF: 
PMAN: 
PTV: 
PPUU: 
PDR: 
PSK: 
PKC: 
PCH: 
PCZ: 
PSOS: 
ACB: 
ABM: 
ABY: 
ABC: 
ABN: 
ABB: 
ABX: 
ABZ: 
ABR: 
ABD: 
ABH: 
ABAD: 
ABJ: 
ABAB: 
ABAJ: 
ABAZ: 
ABK: 
ABAU: 
ABAA: 
ABW: 
ACC: 
ANO: 
ACD: 
ACW: 
ACV: 
AHL: 
PAT: 
MAQ: 
MHC: 
MAD: 
MSX: 
MARI: 
MLQ: 
AMH: 
AMB: 
GAG: 
SAGA: 
MICC: 
AUP74_02724(caiD_2)
CYQ: 
CZA: 
HCH: 
ABO: 
ABO_0987(ech2)
ADI: 
B5T_01798(ech2)
APAC: 
ALN: 
OAI: 
GPB: 
RPJ: 
REU: 
REH: 
H16_A2138(h16_A2138)
CNC: 
RME: 
CBW: 
BPS: 
BPM: 
BPL: 
BPD: 
BPSE: 
BPSM: 
BPSU: 
BPSD: 
BPZ: 
BPQ: 
BPK: 
BPSH: 
BPSA: 
BPSO: 
BUT: 
BTE: 
BTQ: 
BTJ: 
BTZ: 
BTD: 
BTV: 
BTHE: 
BTHM: 
BTHA: 
BTHL: 
BOK: 
BOC: 
BUL: 
BUD: 
AXY: 
AKA: 
RFR: 
RSB: 
ACK: 
ACRA: 
VEI: 
CTT: 
CTES: 
ADN: 
ADK: 
LIH: 
HYR: 
HYB: 
HYL: 
RGE: 
RBN: 
PKT: 
SHD: 
RVA: 
RBM: 
PZU: 
PSF: 
SPHG: 
RCE: 
TMO: 
 » show all
Taxonomy
Reference
1  [PMID:14339651]
  Authors
SEUBERT W, FASS E.
  Title
[STUDIES ON THE BACTERIAL DEGRADATION OF ISOPRENOIDS. IV. THE PURIFICATION AND PROPERTIES OF BETA-ISOHEXENYLGLUTACONYL-COA-HYDRATASE AND BETA-HYDROXY-BETA-ISOHEXENYLGLUTARYL-COA-LYASE.]
  Journal
Biochem. Z. 341 (1964) 23-34.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
UM-BBD (Biocatalysis/Biodegradation Database): 
BRENDA, the Enzyme Database: 
CAS: 
37290-84-9

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