KEGG   ENZYME: 4.2.1.87Help
Entry
EC 4.2.1.87                 Enzyme                                 

Name
octopamine dehydratase;
octopamine hydrolyase;
octopamine hydro-lyase (deaminating)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
1-(4-hydroxyphenyl)-2-aminoethanol hydro-lyase [deaminating; (4-hydroxyphenyl)acetaldehyde-forming]
Reaction(IUBMB)
1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH3 [RN:R03358]
Reaction(KEGG)
Substrate
1-(4-hydroxyphenyl)-2-aminoethanol [CPD:C04227]
Product
4-hydroxyphenylacetaldehyde [CPD:C03765];
NH3 [CPD:C00014]
Comment
The enzyme-catalysed reaction is believed to be dehydration to an enamine, which is spontaneously hydrolysed to an aldehyde and ammonia.
History
EC 4.2.1.87 created 1989
Reference
1  [PMID:3034855]
  Authors
Cuskey SM, Peccoraro V, Olsen RH.
  Title
Initial catabolism of aromatic biogenic amines by Pseudomonas aeruginosa PAO: pathway description, mapping of mutations, and cloning of essential genes.
  Journal
J. Bacteriol. 169 (1987) 2398-404.
  Organism
Pseudomonas aeruginosa PAO1
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
109456-55-5

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