| Entry |
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| Name |
arogenate dehydratase;
carboxycyclohexadienyl dehydratase;
L-arogenate hydro-lyase (decarboxylating)
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| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
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| Sysname |
L-arogenate hydro-lyase (decarboxylating; L-phenylalanine-forming)
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| Reaction(IUBMB) |
L-arogenate = L-phenylalanine + H2O + CO2 [RN: R00691]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| Comment |
Also acts on prephenate and D-prephenyllactate. cf. EC 4.2.1.51, prephenate dehydratase.
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| Pathway |
| Phenylalanine, tyrosine and tryptophan biosynthesis | | Metabolic pathways | | Biosynthesis of secondary metabolites |
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| Orthology |
| cyclohexadienyl dehydratase | | arogenate/prephenate dehydratase |
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| Genes |
ATH: | | ALY: | | GMX: | | MTR: | | CSV: | | RCU: | | POP: | | VVI: | | OSA: | | DOSA: | | BDI: | | SBI: | | ZMA: | | SMO: | | PPP: | | CRE: | | VCN: | | OLU: | | OTA: | | CME: | | MGR: | | PNO: | | PTE: | | ZTR: | | SPT: | | SEK: | | SPQ: | | SEI: | | SEW: | | YPE: | | YPK: | | YPA: | | YPN: | | YPM: | | YPP: | | YPG: | | YPZ: | | YPT: | | YPD: | | YPX: | | YPH: | | YPS: | | YPI: | | YPY: | | YPB: | | EPY: | | EPR: | | EAM: | | EAY: | | EBI: | | ERJ: | | EAE: | | EAR: | | KPN: | | KPU: | | KPP: | | KPE: | | KPO: | | KVA: | | KOX: | | SPE: | | SRR: | | SRS: | | SRA: | | SMAF: | | SMW: | | EIC: | | DDA: | | DDC: | | DDD: | | DZE: | | PAM: | | PLF: | | PAJ: | | PAQ: | | PVA: | | PAO: | | RAH: | | RAQ: | | RAA: | | ROR: | | MSU: | | ASU: | | XCC: | | XCB: | | XCA: | | XCV: | | XCP: | | XAC: | | XAX: | | XAO: | | XAL: | | XCI: | | VVU: | | VVY: | | VVM: | | VPA: | | VPB: | | VHA: | | VEX: | | VEJ: | | VFU: | | VFI: | | VFM: | | VSA: | | PPR: | | PAE: | | PAU: | | PAP: | | PAG: | | PAF: | | PNC: | | PDK: | | PSG: | | PPUU: | | PST: | | PSB: | | PSP: | | PFL: | | PFO: | | PFS: | | PFE: | | PFC: | | PPZ: | | PBA: | | PFV: | | SBL: | | SBS: | | SBB: | | FTW: | | FTL: | | FTH: | | FTA: | | FTS: | | FTI: | | FTM: | | FTN: | | FCF: | | FCN: | | FPH: | | FRT: | | FNA: | | CVI: | | RSO: | | RSC: | | RSL: | | RPI: | | RPF: | | CNC: | | BMA: | | BMV: | | BML: | | BMN: | | BPS: | | BPM: | | BPL: | | BPD: | | BPR: | | BPZ: | | BPQ: | | BTE: | | BVI: | | BUR: | | BCN: | | BCH: | | BCM: | | BCJ: | | BAM: | | BAC: | | BMU: | | BMJ: | | BCT: | | BXE: | | BPH: | | BPY: | | BGL: | | BUG: | | BGE: | | BGF: | | BGD: | | BYI: | | BUK: | | BPX: | | PUT: | | POL: | | AAV: | | AAA: | | ACK: | | VAP: | | VPE: | | HSE: | | CFU: | | DDN: | | PUB: | | PEL: | | PLA: | | SFD: | | ARA: | | AVI: | | BJA: | | BJU: | | BRA: | | BBT: | | BRS: | | AOL: | | AZC: | | MET: | | MNO: | | PSF: | | OAT: | | OAR: | | AZL: | | ALI: | | APC: | | APM: | | ESI: | | EAN: | | BBE: | | GYM: | | SRI: | | MSM: | | MSG: | | MSA: | | NBR: | | SVL: | | SCT: | | SCY: | | SBH: | | AAI: | | NAL: | | SEN: | | PRU: | | IPO: | | SAI: | |
» show all
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| Reference |
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| Authors |
Fischer R, Jensen R. |
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| Title |
Arogenate dehydratase. |
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| Journal |
Methods. Enzymol. 142 (1987) 495-502. |
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| Reference |
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| Authors |
Zamir LO, Tiberio R, Devor KA, Sauriol F, Ahmad S, Jensen RA. |
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| Title |
Structure of D-prephenyllactate. A carboxycyclohexadienyl metabolite from Neurospora crassa. |
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| Journal |
J. Biol. Chem. 263 (1988) 17284-90. |
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| Organism |
Neurospora crassa [GN: ncr] |
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| Reference |
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| Authors |
Siehl DL, Conn EE. |
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| Title |
Kinetic and regulatory properties of arogenate dehydratase in seedlings of Sorghum bicolor (L.) Moench. |
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| Journal |
Arch. Biochem. Biophys. 260 (1988) 822-9. |
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| Organism |
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| Other DBs |
ExplorEnz - The Enzyme Database: IUBMB Enzyme Nomenclature: ExPASy - ENZYME nomenclature database: BRENDA, the Enzyme Database: CAS: 76600-70-9 |
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