KEGG   ENZYME: 4.2.1.98Help
Entry
EC 4.2.1.98                 Enzyme                                 

Name
16alpha-hydroxyprogesterone dehydratase;
hydroxyprogesterone dehydroxylase;
16alpha-hydroxyprogesterone dehydroxylase;
16alpha-dehydroxylase;
16alpha-hydroxyprogesterone hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
16alpha-hydroxyprogesterone hydro-lyase (16,17-didehydroprogesterone-forming)
Reaction(IUBMB)
16alpha-hydroxyprogesterone = 16,17-didehydroprogesterone + H2O [RN:R04166]
Reaction(KEGG)
R04166;
(other) R05174
Show
Substrate
16alpha-hydroxyprogesterone [CPD:C03748]
Product
16,17-didehydroprogesterone [CPD:C03207];
H2O [CPD:C00001]
Comment
16alpha-Hydroxypregnenolone is also a substrate.
History
EC 4.2.1.98 created 1999, modified 2004 (EC 4.2.1.86 created 1989, incorporated 2004)
Reference
1  [PMID:4052439]
  Authors
Glass TL, Lamppa RS.
  Title
Purification and properties of 16 alpha-hydroxyprogesterone dehydroxylase from Eubacterium sp. strain 144.
  Journal
Biochim. Biophys. Acta. 837 (1985) 103-10.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
89287-36-5

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