KEGG   ENZYME: 4.2.3.109Help
Entry
EC 4.2.3.109                Enzyme                                 

Name
(-)-sabinene synthase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranyl-diphosphate diphosphate-lyase [cyclizing, (-)-sabinene-forming]
Reaction(IUBMB)
geranyl diphosphate = (-)-sabinene + diphosphate [RN:R09965]
Reaction(KEGG)
Substrate
geranyl diphosphate [CPD:C00341]
Product
(-)-sabinene [CPD:C20242];
diphosphate [CPD:C00013]
Comment
Requires Mg2+. Isolated from Pinus contorta (lodgepole pine) as cyclase I [1] and from Conocephalum conicum (liverwort) [2].
History
EC 4.2.3.109 created 2012
Reference
1  [PMID:8307957]
  Authors
Savage TJ, Hatch MW, Croteau R
  Title
Monoterpene synthases of Pinus contorta and related conifers. A new class of terpenoid cyclase.
  Journal
J. Biol. Chem. 269 (1994) 4012-20.
Reference
2  [PMID:12941302]
  Authors
Peters RJ, Croteau RB
  Title
Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases.
  Journal
Arch. Biochem. Biophys. 417 (2003) 203-11.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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