KEGG   ENZYME: 4.2.3.142Help
Entry
EC 4.2.3.142                Enzyme                                 

Name
7-epizingiberene synthase [(2Z,6Z)-farnesyl diphosphate cyclizing];
ShZIS (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
(2Z,6Z)-farnesyl-diphosphate lyase (cyclizing; 7-epizingiberene-forming)
Reaction(IUBMB)
(2Z,6Z)-farnesyl diphosphate = 7-epizingiberene + diphosphate [RN:R10284]
Reaction(KEGG)
Substrate
(2Z,6Z)-farnesyl diphosphate [CPD:C19760]
Product
7-epizingiberene [CPD:C20486];
diphosphate [CPD:C00013]
Comment
Isolated from the plant Solanum habrochaites. 7-Epizingiberene is a whitefly repellant.
History
EC 4.2.3.142 created 2013
Reference
1  [PMID:23169639]
  Authors
Bleeker PM, Mirabella R, Diergaarde PJ, VanDoorn A, Tissier A, Kant MR, Prins M, de Vos M, Haring MA, Schuurink RC
  Title
Improved herbivore resistance in cultivated tomato with the sesquiterpene biosynthetic pathway from a wild relative.
  Journal
Proc. Natl. Acad. Sci. U. S. A. 109 (2012) 20124-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 

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